Results 71 to 80 of about 7,156,078 (242)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Antioxidant status and acute phase reactants in pregnant women infected with Plasmodium falciparum

open access: yesRwanda Medical Journal
INTRODUCTION: Malaria during pregnancy remains a public health issue. The most deadly plasmodium, Plasmodium falciparum, kills about 40% of the world's population, especially pregnant women and children under five.
D. Atere Adedeji   +3 more
doaj   +1 more source

Bis(trifluoromethyl)methylene addition to vinyl-terminated SAMs : a gas-phase C–C bond-forming reaction on a surface [PDF]

open access: yes, 2014
The authors acknowledge the Scottish Funding Council for a SPIRIT Studentship (M.A.) and the EPSRC (EP/K000411/1) for financial support, and D.O’H. acknowledges the European Research Council for an Advanced Grant and the Royal Society for a Wolfson ...
Hähner, Georg   +8 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Acute-phase reactants

open access: yesJournal of Oral Research and Review, 2016
The acute-phase response (APR) is a prominent systemic reaction of the organism to local or systemic disturbances in its homeostasis caused by infection, tissue injury, trauma or surgery, or immunological disorders. The tissue macrophage is most commonly
Harpreet Singh Grover   +3 more
doaj   +1 more source

The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients [PDF]

open access: yes, 2001
Background and Objectives. Detection of PML-RAR alpha transcripts by RT-PCR is now established as a rapid and sensitive method for diagnosis of acute promyelocytic leukemia (APL), Although the majority of patients in longterm clinical remission are ...
Gameiro, P   +11 more
core  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Whole blood viscosity assessment issues IV: Prevalence in acute phase inflammation

open access: yes, 2010
Background: Hyperviscosity syndrome has been suggested as not simply an acute reaction. Yet, erythrocyte sedimentation rate is associated with whole blood viscosity and it is an indirect acute phase inflammation marker.
Nwose, Ezekiel Uba
core   +1 more source

The acute phase protein response to intramammary infection in water buffalo (Bubalus bubalis)

open access: yes, 2010
Acute phase proteins are a group of serum proteins that change their concentration in animals following infection, inflammation or stress. Serum amyloid A (SAA) and α1-acid glycoprotein (AGP) are regarded as acute phase proteins in bovine, and their ...
P. Sartorelli   +7 more
core   +2 more sources

Proteomic profiling of the plasma of Gambian children with cerebral malaria

open access: yesMalaria Journal, 2018
Background Cerebral malaria (CM) is a severe neurological complication of Plasmodium falciparum infection. A number of pathological findings have been correlated with pediatric CM including sequestration, platelet accumulation, petechial haemorrhage and ...
Ehab M. Moussa   +10 more
doaj   +1 more source

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