Orientia tsutsugamushi in Eschars from Scrub Typhus Patients
To verify the value of eschars for the diagnosis of scrub typhus and to characterize genotypes of Orientia tsutsugamushi in patients, we examined eschars and blood specimens of 7 patients from Shandong Province, People's Republic of China, for O ...
Yun-Xi Liu +6 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
A multimodal approach to ameliorate acute phase reaction induced by zoledronic acid
Chung-Hwan Chen +4 more
doaj +1 more source
Systemic cytokines related to memory function 6–9 months and 12–15 months after SARS-CoV-2 infection
Cognitive symptoms persisting beyond the acute phase of COVID-19 infection are commonly described for up to 2 years after infection. The relationship between cognitive performance, in particular episodic memory processes observed chronically after ...
A. Nuber-Champier +18 more
doaj +1 more source
Eosinophilic myocarditis presenting as acute coronary syndrome
Eosinophilic myocarditis (EM) is a rare condition that may result from several heterogeneous eosinophilic diseases, including parasite infection, hypersensitivity reaction, vasculitis, and hypereosinophilic syndrome.
Evrim Şimşek +2 more
doaj +1 more source
Acute and specialist health services more than a hospital, a strategic plan 1998-2006, final report
The purpose of this report is to articulate an appropriate mix of services for Acute and Specialist Health Care in the Northern Territory. It represents the outcome from consultation with over 500 interested stakeholders throughout the Northern Territory
Acute and Specialist Care Branch
core
Estimated glomerular filtration rate correlates poorly with four-hour creatinine clearance in critically ill patients with acute kidney injury. [PDF]
Introduction. RIFLE and AKIN provide a standardised classification of acute kidney injury (AKI), but their categorical rather than continuous nature restricts their use to a research tool. A more accurate real-time description of renal function in AKI is
Iain A. M. MacPhee +5 more
core +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Acute hospitals divison: operational plan 2014 [PDF]
The implementation of the Government’s decision to re-organise the acute hospitals system will be guided by the Department of Health’s Future Health – A Strategic Framework for Reform of the Health Service 2012-2015. The Health Service strategic reform
Health Service Executive (HSE), Acute Hospitals Division
core

