Results 111 to 120 of about 26,607 (237)

Changes in White Blood Cell and Neutrophil Counts in Patients With Schizophrenia Treated With Lithium Carbonate, Adenine, and Ninjin‐Yoei‐To: A Preliminary Study

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Thirty‐five patients with schizophrenia who received adenine, Ninjin‐yoei‐to, or lithium carbonate were included in the treatment group. Eighty‐one patients with schizophrenia comprised the control group. In the two‐way mixed ANOVA, treatment increased white blood cell and neutrophil counts in patients with schizophrenia, particularly from 2 months ...
Teruyuki Matsuoka, Sumihiro Yamano
wiley   +1 more source

The helicase HAGE prevents interferon-a-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1

, 2014
The tumour suppressor PML (promyelocytic leukaemia protein) regulates several cellular pathways involving cell growth, apoptosis, differentiation and senescence.
Regad, T, Mathieu, MG, Miles, AK, Buczek, ME, Ahmad, M, Rees, RC, Pockley, AG   +6 more
core   +1 more source

Pattern of Expression of PML-RARα Transcripts in Acute Promyelocytic Leukemia Patients and Its Correlation with Overall Survival: A Retrospective Study from Western India

Indian Journal of Medical and Paediatric Oncology
Introduction Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia with specific molecular pathogenesis, clinical features, and treatment. It is cytogenetically characterized by translocation t (15;17) (q24;q21).
Shweta Gondha, Prerna Walia, Beena Brahmbhatt, Jayendrakumar Patel, Toral Mandalia, Disha Jethva   +5 more
doaj   +1 more source

Multiplexed Transcriptomics for Screening Drug Combinations and Defining the Mechanism of Action of HCC Therapeutics at Single‐Cell Resolution

Cell Proliferation, Volume 59, Issue 6, June 2026.
We designed a framework for screening clinical drug combinations with anti‐hepatocellular carcinoma (HCC) activity, comprising four parts: primary screening, single‐cell screening, functional validation, and mechanism research. High‐throughput single‐cell screening identifies HY (HHT and YM155) as a potent anti‐HCC drug combination, validated by in ...
Mengmeng Jiang, Haide Chen, Guoxia Wen, Yuqing Mei, Wenzhao Zhou, Bin Xu, Tingyue Zhang, Guangyan Li, Junqing Wu, Xiaoping Han, Xudong Fu, Guoji Guo, Jingjing Wang   +12 more
wiley   +1 more source

Immunorecognition of leukemic stem cells by NK cells : the role of HDAC inhibitors in NKG2D ligand-mediated anti-tumor responses in acute myeloid leukemia [PDF]

, 2008
The diagnosis of acute myeloid leukemia (AML) is associated to a poor long-term outcome due to frequent relapse despite intensive chemotherapy, radiation and hematopoietic stem cell transplantation (HSCT) as well as continuous advances in treatment ...
Langenkamp, Ulrich
core   +1 more source

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, Volume 48, Issue 3, Page 521-530, June 2026.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source

Status epilepticus and acute promyelocytic leukemia

, 2017
Neurological manifestations are rare as initial presentation in acute promyelocytic leukemia (APL). This case illustrates status epilepticus as initial presentation in this disease.
Sunil Kumar Garg, Pragya Garg
core   +1 more source

Estudo da associação de genes e proteínas de resistência a múltiplos fármacos (abcb1/ABCB1, abcc1/ABCC1 e lrp/LRP) com marcadores moleculares em pacientes portadores de leucemias agudas [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2013.Menos de 45% dos portadores de leucemias agudas (LAs) sobrevivem cinco anos após o diagnóstico. O insucesso
Moraes, Ana Carolina Rabello de
core  

Metaphase and Interphase Cytogenetics with Alu-PCR-amplified Yeast Artificial Chromosome Clones Containing the BCR Gene and the Protooncogenes c-raf-1, c-fms, and c-erbB-21 [PDF]

, 1992
A human yeast artificial chromosome (YAC) library was screened by polymerase chain reaction with oligonucleotide primers defined for DNA sequences of the BCR gene and the protooncogenes c-raf-1, c-fms, and c-erB-2.
Olson, Maynard V., Riethman, Harold C., Green, Eric D., Becher, Reinhard, Taniwaki, Masafumi, Michael R. Speicher, Speicher, Michael R., Cremer, Thomas, Christoph Lengauer, Eric D. Green, Konecki, David, Maynard V. Olson, David Konecki, Reinhard Becher, Harold C. Riethman, Lengauer, Christoph, Masafumi Taniwaki, Thomas Cremer   +17 more
core  

Novel strategies in treatment of acute promyelocytic leukemia

, 2012
Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia characterized by t(15;17) and a life-threatening coagulopathy. Once highly fatal, nowadays standard treatment approaches with all-trans retinoic acid (ATRA) along with chemotherapy
Cicconi, L., F Lo-Coco, L Cicconi, Cicconi, L, Lo Coco, F, LO COCO, FRANCESCO   +5 more
core   +1 more source