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Acute promyelocytic leukemia in childhood
Current Oncology Reports, 2009Acute promyelocytic leukemia (APL) is a relatively rare form of acute myelogenous leukemia (AML). In the United States, APL in children constitutes only 5% to 10% of AML. Molecularly, the disease is characterized by a fusion protein, promyelocytic leukemia (PML)-retinoic acid receptor (RAR)-alpha that results from a balanced reciprocal translocation ...
John, Gregory, James, Feusner
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Acute myeloid leukemia management and research in 2025
CaThe first 5 decades of research in acute myeloid leukemia (AML) were dominated by the cytarabine plus anthracyclines backbone, with advances in strategies including allogeneic hematopoietic stem cell transplantation, high‐dose cytarabine, supportive care
H. Kantarjian +9 more
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Management of patients with acute promyelocytic leukemia
Leukemia, 2018S. Kayser, R. Schlenk, U. Platzbecker
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Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-Vornhagen +2 more
exaly
[Acute promyelocytic leukemia].
[Rinsho ketsueki] The Japanese journal of clinical hematology, 2013Yuka, Harada, Hironori, Harada
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History of Acute Promyelocytic Leukemia
2017Within a 60-year time span, the most severe acute leukemia—termed acute promyelocytic leukemia (APL) by the Norwegian author Leif Hillestad—was identified, characterized, and cured. The determination of a precise molecular definition of the genetic defect and the emergence of an antidogmatic paradigm have made the history of APL a model for the ...
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