FPR1 affects acute rejection in kidney transplantation by regulating iron metabolism in neutrophils [PDF]
Background Acute rejection (AR) is one of the significant factors contributing to poor prognosis in patients following kidney transplantation. Neutrophils are the main cause of early host-induced tissue injury.
Peiyuan Li +8 more
doaj +2 more sources
Microcirculatory Dysfunction and Its Role in Diagnosing Acute Rejection in Pediatric Heart Transplantation: A Pilot Study [PDF]
Background/Objectives: Acute rejection remains a major challenge in pediatric heart transplantation (HT), with limited tools for early diagnosis.
Borja Rivero-Santana +8 more
doaj +2 more sources
Expression of CD40 ligand, interferon-gamma and Fas ligand genes in endomyocardial biopsies of human cardiac allografts: correlation with acute rejection [PDF]
The purpose of the present study was to investigate the expression (mRNA) of CD40 ligand (CD40L), interferon-gamma (IFN-gamma) and Fas ligand (FasL) genes in human cardiac allografts in relation to the occurrence of acute cardiac allograft rejection as ...
N. Shulzhenko +8 more
doaj +4 more sources
Quilty Lesions in the Endomyocardial Biopsies after Heart Transplantation [PDF]
Background The aim of this study was to investigate the clinical significance of Quilty lesions in endomyocardial biopsies (EMBs) of cardiac transplantation patients.
Haeyon Cho +3 more
doaj +1 more source
Identification of common blood gene signatures for the diagnosis of renal and cardiac acute allograft rejection. [PDF]
To test, whether 10 genes, diagnostic of renal allograft rejection in blood, are able to diagnose and predict cardiac allograft rejection, we analyzed 250 blood samples from heart transplant recipients with and without acute rejection (AR) and with ...
Hsieh, Szu-Chuan +9 more
core +5 more sources
The value of urine cytologic examination findings in the diagnosis of the acute renal allograft rejection [PDF]
Background. Acute rejection of allograft is one of the most serious complications of renal transplantation that requires fast and precise diagnostic approach.
Tatomirović Željka +5 more
doaj +1 more source
Perturbations of the T-cell immune repertoire in kidney transplant rejection
In this cross-sectional and longitudinal analysis of mapping the T-cell repertoire in kidney transplant recipients, we have investigated and validated T-cell clonality, immune repertoire chronology at rejection, and contemporaneous allograft biopsy ...
Tara K. Sigdel +9 more
doaj +1 more source
Experimental diabetes exacerbates skin transplant rejection in rats [PDF]
PURPOSE: To investigate the effect of chronic experimental diabetes on skin allografts in rats as a simple model that could clarify some basic aspects and mechanisms involved in transplant rejection in diabetes compared to normal animals.
Flávio Pola dos Reis +2 more
doaj +3 more sources
Heparan sulfate is a plasma biomarker of acute cellular allograft rejection. [PDF]
Despite advances in management of immunosuppression, graft rejection remains a significant clinical problem in solid organ transplantation. Non-invasive biomarkers of graft rejection can facilitate earlier diagnosis and treatment of acute rejection.
Andrew S Barbas +6 more
doaj +1 more source
Although the incidence of acute antibody mediated rejection in liver transplantation is low, the consequences of acute antibody mediated rejection can be devastating, often leading to severe fibrotic changes and early graft loss.
Michie A. Adjei +10 more
doaj +1 more source

