CD16+ monocytes and skewed macrophage polarization toward M2 type hallmark heart transplant acute cellular rejection [PDF]
Background: During acute heart transplant rejection, infiltration of lymphocytes and monocytes is followed by endothelial injury and eventually myocardial fibrosis.
Baan, C.C. (Carla) +9 more
core +3 more sources
The impact of early acute rejection on kidney graft survival after repeat kidney transplantation
Introduction. Despite the improvements in immunosuppressive therapy, the growing number of repeat kidney transplantations and associated risks of acute rejection make it relevant to assess the impact of early acute rejection on a long-term kidney graft ...
A. V. Pinchuk +5 more
doaj +1 more source
An Analysis of Early Renal Transplant Protocol Biopsies - the High Incidence of Subclinical Tubulitis [PDF]
To investigate the possibility that we have been underestimating the true incidence of acute rejection, we began to perform protocol biopsies after kidney transplantation. This analysis looks at the one-week biopsies. Between March 1 and October 1, 1999,
Burdick +16 more
core +1 more source
Acute rejection is a major risk factor for chronic allograft injury (CAI). Blood leukocytes interacting with allograft endothelial cells during acute rejection were suggested to contribute to the still enigmatic pathogenesis of CAI.
Anna Zakrzewicz +3 more
doaj +1 more source
Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys [PDF]
We transplanted kidneys from α1,3-galactosyltransferase knockout (GalT-KO) pigs into six baboons using two different immunosuppressive regimens, but most of the baboons died from severe acute humoral xenograft rejection. Circulating induced antibodies to
Anthony Jevnikar +33 more
core +1 more source
Pathways to Acute Humoral Rejection [PDF]
Acute humoral rejection, also known as acute vascular rejection, is a devastating condition of organ transplants and a major barrier to clinical application of organ xenotransplantation. Although initiation of acute humoral or vascular rejection is generally linked to the action of antibodies and complement on the graft, other factors such as ischemia,
Soheyla, Saadi +3 more
openaire +2 more sources
Intragraft interleukin 2 mRNA expression during acute cellular rejection and left ventricular total wall thickness after heart transplantation [PDF]
OBJECTIVE: To assess whether diastolic graft function is influenced by intragraft interleukin 2 (IL-2) messenger RNA (mRNA) expression in rejecting cardiac allografts.
Baan, C.C. (Carla) +8 more
core +1 more source
Levels of serum- and urinary-neopterin and serum-IL-6 and IL-6R of kidney transplant recipients "Were higher in acute rejection episode than in stable condition. IL-8 serum levels had risen prior to clinical diagnosis of acute rejection episode.
Miki Tsuneharu +2 more
doaj +1 more source
THE DIAGNOSIS OF LIVER ALLOGRAFT ACUTE REJECTION IN LIVER BIOPSIES
We performed histological examination of 80 liver allograft biopsies, the diagnosis of acute rejection was proved in 34 cases. Histological changes in liver biopsies in different grades of acute rejection were estimated according to Banff classification ...
L. V. Shkalova +5 more
doaj +1 more source
The effect of small bowel transplantation on the morphology and physiology of intestinal muscle: A comparison of autografts versus allografts in dogs [PDF]
The effects of acute (AR) and chronic rejection (CR) on intestinal smooth muscle that are responsible for the dysmotility following small bowel transplantation (SBTX) are incompletely understood. Jejunal and ileal specimens from normal control dogs (n=7),
Bauer, AJ +6 more
core +1 more source

