Results 91 to 100 of about 4,908,147 (289)

Renal complications in acute leukemias

open access: yesHaematologica, 1998
BACKGROUND AND OBJECTIVE: Renal failure is a known complication of acute leukemias both at diagnosis and following cytostatic treatment. No recent studies give data on the incidence and risk factors of renal complications and their prognostic impact ...
R Munker   +4 more
doaj  

Acute renal failure and normal blood count: A rare presentation of T-cell acute lymphoblastic leukemia

open access: yesLeukemia Research Reports, 2014
A 10-year-old boy presented with headache and visual disturbance. During work-up in hospital he developed acute renal failure with a maximum creatinine level of 534 μmol/l. Complete blood count was normal.
Peter H. Asdahl   +3 more
doaj   +1 more source

Do acute elevations of serum creatinine in primary care engender an increased mortality risk? [PDF]

open access: yes, 2014
Background: The significant impact Acute Kidney Injury (AKI) has on patient morbidity and mortality emphasizes the need for early recognition and effective treatment.
Paul Bassett   +13 more
core   +2 more sources

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

open access: yesAdvanced Science, EarlyView.
A disease‐stage synchronized nanozyme platform is developed to treat polymicrobial sepsis by adapting its functions to changing infection environments. The system eliminates multidrug‐resistant bacteria during early infection while reducing inflammation and restoring immune balance during recovery, providing an integrated strategy for infection control
Anlai Zou   +11 more
wiley   +1 more source

Acute renal failure in the cardiac intensive care unit – A practical approach to management

open access: yesSA Heart Journal, 2017
The association between cardiovascular disease and acute renal failure (ARF) and acute-on-chronic renal failure is less well defined. In the cardiac intensive care unit (CICU), the presence of ARF imparts a significant mortality.
Geoffrey Bihl, Thomas Mabin, Derek Fine
doaj   +1 more source

A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle

open access: yesAdvanced Science, EarlyView.
This study identified a mitochondrial micropeptide encoded by a non‐canonical open reading frame (alt‐ORF) within the CTSB gene. This micropeptide named APPM (ATP production‐promoting micropeptide) is a novel component of the OGDHc complex in the TCA cycle. APPM localizes to the inner mitochondrial membrane and directly binds to OGDH, the E1 subunit of
Xinqiang Yin   +9 more
wiley   +1 more source

Acute Renal Failure

open access: yes, 2007
Includes descriptive metadata provided by producer in MP3 file: "Surgery ICU Rounds - Podcasts - Acute RenalFailure."Acute renal failure is a dreaded complication in the ICU.
Guy, Jeffrey S.
core  

p300‐Mediated H3K18 Lactylation Drives Radiation‐Induced Pulmonary Fibrosis via VIRMA‐Dependent m6A Modification of GATA3

open access: yesAdvanced Science, EarlyView.
Radiation triggers glycolytic reprogramming in alveolar epithelial type II cells, causing pathological lactate accumulation. This metabolic stress drives p300‐mediated H3K18 lactylation at the VIRMA promoter, activating transcription. Elevated VIRMA enriches m6A on GATA3 mRNA, which YTHDF1 stabilizes, ultimately driving epithelial–mesenchymal ...
Junxuan Yi   +8 more
wiley   +1 more source

Mineral Metabolism in Acute Renal Failure

open access: yes
Disturbances in divalent ion metabolism are well known consequences of chronic renal failure (CRF). An in-depth review of the recent extensive literature about these disturbances is beyond the scope and goals of this chapter.
Strauss, José   +2 more
core   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu   +10 more
wiley   +1 more source

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