Results 141 to 150 of about 1,197,646 (376)

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

Advanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun, Yihang Yuan, Qian Qiu, Kexuan Tan, Xutong Li, Haotian Li, Luyang Kang, Yuting Gu, Ziheng Zhang, Jiayu He, Jiali Li, Junjie Lin, Zihan Xie, Kexing Han, Jiabin Li, Yang Zhang, Ting Wu, Yufeng Gao   +17 more
wiley   +1 more source

Severe renal failure in acute bacterial pyelonephritis: Do not forget corticosteroids

Saudi Journal of Kidney Diseases and Transplantation, 2010
Acute renal failure (ARF) is a rare complication of acute pyelonephritis in adult immunocompetent patients. Recovery of renal function usually occurs if antibiotics are promptly initiated.
Sqalli Tarik, Hamzaoui Hakim, Guiard Elsa, Noel Laure-Helene, Fakhouri Fadi   +4 more
doaj  

Calcium-binding proteins annexin A2 and S100A6 are sensors of tubular injury and recovery in acute renal failure [PDF]

, 2005
Chao‐Wen Cheng, Abdalla Rifai, Shuk‐Man Ka, Hao‐Ai Shui, Yuh‐Feng Lin, Wei‐Hwa Lee, Ann Chen   +6 more
openalex   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source

Anemia and Thrombocytopenia in Acute and Chronic Renal Failure

International Journal of Hematology-Oncology and Stem Cell Research, 2013
Background: Acute renal failure describes as a syndrome by rapid decline in the ability of the kidney to eliminate waste products, regulate acid–base balance, and manage water homeostasis.
Akbar Dorgalaleh, Mohammad Mahmudi, Shadi Tabibian, Zahra Kashani Khatib, Gholam Hossein Tamaddon, Esmaeil Sanei Moghaddam, Taregh Bamedi, Shaban Alizadeh, Eshagh Moradi   +8 more
doaj  

Acute Necrotizing Myopathy and Acute Renal Failure in Association with Acute Severe Asthma [PDF]

, 1994
Michael J. O’Leary, Mrinalini Honavar, J. H. Coakley   +2 more
openalex   +1 more source

Incidence and Prognostic Importance of Acute Renal Failure After Percutaneous Coronary Intervention

Circulation, 2002
C. Rihal, S. Textor, D. Grill, P. Berger, H. Ting, P. Best, Mandeep Singh, M. Bell, G. Barsness, V. Mathew, K. Garratt, D. Holmes   +11 more
semanticscholar   +1 more source

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

Rupestonic Acid of Artemisia Rupestris L. Extract Treats Pulmonary Fibrosis in COPD by Targeting TGF‐β1

Advanced Science, EarlyView.
RA of EEAR inhibits TGF‐β1 ubiquitination and changes conformation by target binding TGF‐β1, regulating TGF‐β1/Smad2/3 signaling pathway. Thus it down‐regulated downstream protein expression, inhibited EMT and collagen deposition of ECM, in order to EEAR preventing PF in COPD.
Lingfeng Peng, Lulu Zhang, Yimeng Fan, Sijuan Huang, Qingyu Zhao, Chao Han, Zhihui Hao   +6 more
wiley   +1 more source

Transient acute renal failure after coronary thrombolysis with streptokinase

, 2021
Rodolfo Vega Candelario, Junior Vega Jiménez   +1 more
openalex   +1 more source