Results 111 to 120 of about 87,305 (225)

Coix Seed Attenuates Acute Lung Injury via NLRP3 Signaling Pathway: Efficacy, Active Components, and Mechanisms

open access: yesFood Science &Nutrition, Volume 14, Issue 9, September 2026.
From component identification to target validation: Coix seed extract exerts a protective effect against acute lung injury (ALI) by synergistically inhibiting inflammatory cytokines and NLRP3‐mediated pyroptosis through multiple signaling pathways. ABSTRACT Coix seed is a medicinal and nutritional resource, but its protective effects against acute lung
Qi Yan   +7 more
wiley   +1 more source

Causes and Contributing Factors of In‐Hospital and Post‐Discharge Mortality Among Patients With Severe Acute Respiratory Infection in Low‐ and Middle‐Income Countries: A Scoping Review

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Severe acute respiratory infections (SARI) remain a major cause of global morbidity and mortality, with a disproportionate burden in low‐ and middle‐income countries (LMICs). Although in‐hospital mortality is frequently reported, deaths occurring after hospital discharge remain poorly documented.
Md Ariful Islam   +7 more
wiley   +1 more source

Early prediction of multiple organ failure for sepsis patients based on machine learning algorithms

open access: yesJournal of Intelligent Medicine, Volume 3, Issue 3, Page 277-289, September 2026.
Abstract In recent years, there has been a notable rise in sepsis incidence leading to more multiple organ failure and higher mortality. The lack of effective treatments for sepsis highlights the importance of early prediction in preventing multiple organ failure. This study aimed to develop a model for the early prediction of multiple organ failure in
Runnan He   +11 more
wiley   +1 more source

LncRNA NORAD Enhances Inflammatory Injury in Sepsis‐Associated Acute Lung Damage Through miR‐150‐5p/STAT1‐Dependent NF‐κB Activation

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 9, September 2026.
ABSTRACT Acute lung injury (ALI) is a severe complication of sepsis, yet the role of lncRNA NORAD in its pathogenesis remains unclear. Using LPS‐stimulated BEAS‐2B and HBEC3‐KT cells as well as cecal ligation and puncture (CLP)‐induced ALI models in C57BL/6 mice, we found that NORAD expression was markedly upregulated and promoted cell injury ...
Han Liu   +4 more
wiley   +1 more source

Restricted TCR Diversity and Expansion of CD177+CD8+ and TLR4+CD4+T Cell Subsets in Septic Shock‐Associated Immunosuppression: A Single‐Cell Multi‐Omics Study

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Our study enrolled 10 septic shock patients with immunosuppression and 10 healthy controls and sorted CD8+ and CD4+ T cells for transcriptome sequencing. Disease‐specific cell types, key transcripts, and TCR features were identified using integrated analysis.
Yawen Xie   +6 more
wiley   +1 more source

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