Results 91 to 100 of about 1,201,249 (376)

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Non-invasive Ventilation in Acute Respiratory Failure

Acta Medica Indonesiana, 2014
One of the cornerstones of critical care medicine is support of the failing respiratory system. The 2 major components of managing respiratory failure are the acute intervention and the weaning process.
Gurmeet Singh, Ceva W Pitoyo
doaj   +6 more sources

Automatic adjustment of noninvasive pressure support with abilevel home ventilator in patients with acute respiratory failure: afeasibility study [PDF]

, 2018
Objective: To test the feasibility of applying noninvasive ventilation (NIV) using aprototype algorithm implemented in abilevel ventilation device designed to adjust pressure support (PS) to maintain aclinician-set alveolar ventilation in patients with ...
Bassin, David, Battisti, Anne, Jolliet, Philippe, Tassaux, Didier   +3 more
core  

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Noninvasive positive pressure ventilation in acute respiratory failure due to COPD vs other causes: Effectiveness and predictors of failure in a respiratory ICU in North India

International Journal of COPD, 2008
Ritesh Agarwal, Rajesh Gupta, Ashutosh N Aggarwal, Dheeraj GuptaDepartment of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaObjectives: To determine the effectiveness of noninvasive positive pressure ...
Ritesh Agarwal, Rajesh Gupta, Ashutosh N Aggarwal, Dheeraj Gupta   +3 more
doaj  

Management of mechanical ventilation in acute severe asthma: practical aspects [PDF]

, 2018
Background: Acute severe asthma induces marked alterations in respiratory mechanics, characterized by acritical limitation of expiratory flow and aheterogeneous and reversible increase in airway resistance, resulting in premature airway closure, lung ...
Feihl, François, Oddo, Mauro, Perret, Claude, Schaller, Marie-Denise   +3 more
core  

Acute respiratory failure in pregnancy [PDF]

Obstetric Medicine, 2015
Respiratory failure affects up to 0.2% of pregnancies, more commonly in the postpartum period. Altered maternal respiratory physiology affects the assessment and management of these patients. Respiratory failure may result from pregnancy-specific conditions such as preeclampsia, amniotic fluid embolism or peripartum cardiomyopathy.
openaire   +3 more sources

Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study*

Critical Care Medicine, 2019
Objectives: To describe the characteristics and outcomes of patients with acute respiratory distress syndrome with or without spontaneous breathing and to investigate whether the effects of spontaneous breathing on outcome depend on acute respiratory ...
F. V. van Haren, T. Pham, L. Brochard, G. Bellani, J. Laffey, M. Dres, E. Fan, E. Goligher, L. Heunks, Joan M. Lynch, H. Wrigge, D. McAuley   +11 more
semanticscholar   +1 more source

Highly Sensitive Cuffless Blood Pressure Monitoring with Selective Laser‐Sintered Liquid Metal Conductors

Advanced Functional Materials, EarlyView.
A soft, compact, and cuffless system for continuous blood pressure monitoring using laser‐sintered liquid metal conductors is developed. The stretchability and sensitivity of the device enable real‐time, non‐invasive tracking of blood pressure, including recovery after exercise. This wearable device offers a practical solution for managing hypertension
Jung Jae Park, Sangwoo Hong, Yeongju Jung, Phillip Won, Carmel Majidi, Minwoo Kim, Seung Hwan Ko   +6 more
wiley   +1 more source