Results 111 to 120 of about 401,782 (243)

Exploring Functionally Enhanced BLP‐Trained Macrophage Subpopulations in S. Aureus Infection: Underlying Mechanisms and Therapeutic Significance

open access: yesAdvanced Science, EarlyView.
BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan   +13 more
wiley   +1 more source

Postoperative noninvasive ventilation

open access: yesZdravniški Vestnik, 2010
Backround: Patients with acute respiratory failure often require endotracheal intubation and mechanical ventilation. Non-invasive ventilation (NIV) means ventilation without an artificial airway – endotracheal tubus or tracheostomy canulla.
Lucija Oberauner   +4 more
doaj  

Nocturnal non-invasive ventilation in COPD patients with prolonged hypercapnia after ventilatory support for acute respiratory failure: a randomised, controlled, parallel-group study [PDF]

open access: bronze, 2014
Fransien Struik   +8 more
openalex   +1 more source

Skullcapflavone II Inhibits SLC1A4‐Mediated L‐Serine Uptake and Promotes Mitochondrial Damage in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Skullcapflavone II (SkII) significantly alters serine metabolism in gastric cancer cells by directly targeting the L‐serine transporter SLC1A4, thereby inhibiting L‐serine uptake rather than de novo synthesis. This disruption of serine metabolism by SkII leads to increased oxidative stress and consequent mitochondrial damage.
Jing Zhao   +10 more
wiley   +1 more source

Reply to: Diaphragm excursion and diaphragm thickening fraction: commonality and conflict

open access: yesEuropean Respiratory Review
Diego Poddighe   +5 more
doaj   +1 more source

Extracorporeal membrane oxygenation in immunocompromised patients with acute respiratory failure: A retrospective cohort study [PDF]

open access: gold, 2023
Ye Tian   +11 more
openalex   +1 more source

Type II Alveolar Epithelial Cells Promote Sepsis‐Induced Immunosuppression in Alveolar Macrophages via Exosomal lncRNA Rmrp Release

open access: yesAdvanced Science, EarlyView.
The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu   +17 more
wiley   +1 more source

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