Results 151 to 160 of about 881,734 (348)

Airway occlusion pressure (P0.1) — A useful predictor for the weaning outcome in patients with acute respiratory failure — [PDF]

, 1990
Kazufumi Okamoto, Toshihide Sato, Tohru Morioka   +2 more
openalex   +1 more source

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

Advanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu, Guoqing Jing, Shujuan Wu, Min Yuan, Yingyue Dong, Xue Chen, Huimin Zhou, Hailong Gong, Jing Zuo, Xiaojing Wu, Xuemin Song   +10 more
wiley   +1 more source

Leptospirosis as a cause of acute respiratory failure: clinical features and outcome in 35 critical care patients

Brazilian Journal of Infectious Diseases, 2002
Leptospirosis may have important complications, such as acute respiratory failure (ARF) associated or not with other organic dysfunction, with a high mortality rate. We report the characteristics and evolution of severe leptospirosis associated with ARF.
Vieira Silvia R R, Brauner Janete S
doaj  

Brain‐Wide Spatiotemporally Distinct Traveling Waves Drive Anxiety‐Like Behaviors in Mice

Advanced Science, EarlyView.
J.Liu et al. reveal the complete propagation dynamics of cortical traveling waves, from local circuitry initiation to long‐range propagation, and identify their functional relevance in modulating anxiety‐like behaviors and underlying cellular neuroplasticity in mice.
Jiaming Liu, Jia‐Wen Mo, Xunda Wang, Yinuo Ma, Shile Tian, Qi Wang, Peng‐Li Kong, Ziqi An, Li Ding, Jing Ren, Cheng‐Lin Lu, Chuanjun Tong, Ed X. Wu, Qiu‐gen Hu, Xiong Cao, Yanqiu Feng   +15 more
wiley   +1 more source

Respiratory response to CO2 in patients with chronic obstructive pulmonary disease in acute respiratory failure [PDF]

, 1993
Catherine Tardif, G. Bonmarchand, JF Gibon, M.F. Hellot, J Leroy, P Pasquis, J. Milic‐Emili, Derenne Jp   +7 more
openalex   +1 more source

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Advanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen   +13 more
wiley   +1 more source

Acute/Chronic respiratory failure [PDF]

, 1992
C. De La Cruz, A. Criado, L. Diaz, A. Seiz, P. L. Vidaur, J. R. Fraile, Kriton S. Filos, Leonidas C. Goudas, D. Dougenis, Vassilios Tassoudis, Ourania Patroni, Walther‐Benedikt Winkler, R Karnik, O. Seelmann, J. Havlicek, J. Stany, H. Becker, J. H. Peter, W. Pitzer, Heiko Schneider, P. von Wichert, R. A. De Blasi, Giorgio Conti, Consalvo Mattia, A. M. Mega, Marco Ferrari, A Gasparetto, H. Steltzer, M. Hiesmayr, P. Krafft, R. Petcold, Kathrin Strasser, A. F. Hammerle, G. Capellier, Shinta Liauw, T. Wintoh, John C. Marshall, Wilfred Demajo, F Barale, P M Walker, Thierry Dugernier, P. F. Laterre, G. Deby‐Dupont, Maurice Lamy, Marc Reynaert, P. Navarrete, Guillermo Vázquez, Ramón Rivera Espinosa, Erlinda Fernández, A. Mérida, Johannes Boch, K. Eibenberger, Christian Herold, W Schlick, R. M. J. L. van der Heijde, Hans Grotjohan, A. Versprille, C. A. Wagenvoort, Pieter G. Raijmakers, A. B. J. Groeneveld, A. J. Schneider, Han Rauwerda, G. J. J. Teule, L. G. Thija, Morley M. Singer, Joost S.P. Vermaat, G.M. Hall, G. Latter, Manish M. Patel, J. R. C. Jansen, F. Bordet, A. Mercatello, B. Coronel, M. Bret, J. D. Tlgaud, E. Archimbaud, J. F. Moskovtchenko, L. Gregorakos, Ch. Katsanos, Argyris Michalopoulos, V. Malessios, D. Mavropanou, J. Nicolopoulos, Klimentini E. Karageorgiou, E. Tognet, P. Huici Polo, Yves Devaux, D Fière, Päivi Valta, J. Takala, Francesco De Blasio, E. Iannuzzi, A. De Sio, Fausto Ferraro, Fernando Schiraldi, G Mostarda, N. Spannbrucker, U. Kiesow, R. Kleinschmidt, P. Reper   +99 more
openalex   +1 more source

Cathepsin K Aggravates Pulmonary Fibrosis Through Promoting Fibroblast Glutamine Metabolism and Collagen Synthesis

Advanced Science, EarlyView.
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen, Xiaoxiao Meng, Yong Zhu, Dapeng Wang, Mengmeng Wang, Ziyuan Wang, Xue Tian, Jiaxiang Zhang, Zhiying Yue, Zhengfeng Yang, Ruilan Wang   +10 more
wiley   +1 more source

Reply to: Diaphragm excursion and diaphragm thickening fraction: commonality and conflict

European Respiratory Review
Diego Poddighe, Alexandros Kalkanis, Dries Testelmans, Greet Hermans, Daniel Langer, on behalf of all authors of “Respiratory muscle dysfunction in acute and chronic respiratory failure: how to diagnose and how to treat?”   +5 more
doaj   +1 more source

Non-invasive mechanical ventilation in acute respiratory failure due to chronic obstructive pulmonary disease: correlates for success. [PDF]

, 1995
Nicolino Ambrosino, K Foglio, F Rubini, Enrico Clini, Stefano Nava, Michele Vitacca   +5 more
openalex   +1 more source