Results 171 to 180 of about 702,501 (295)

Optimal Grazing Exclusion Duration to Enhance Soil Carbon Sequestration in Degraded Grasslands

Advanced Science, EarlyView.
Across China, grazing exclusion reaches the national mean soil organic carbon recovery benchmark sooner in high‐MAP regions (> 500 mm), but recovery is much slower where MAP < 300 mm. Scaling this strategy to 70% of China's degraded grasslands would sequester about 1.52 Pg of soil carbon over 10 years—roughly 17% of annual global fossil‐fuel emissions.
Bin Zhang, Chongzhi Sun, Dongmei Xue, Paul Christiaan Struik, Tongrui Zhang, Jiayue Liu, Tingting Xing, Ziyang Liu, Shiming Tang, Ke Jin   +9 more
wiley   +1 more source

In-hospital testing of NIVPredict - an AI tool for early prediction of non-invasive ventilation outcome in acute respiratory failure. [PDF]

Crit Care
Yu H, Saffaran S, Ali A, Henry C, Mustfa N, Thomas A, Rajhan A, Isrhad S, Weaver L, Tonelli R, Menga LS, Zhang Q, Samadi ME, Schuppert A, Laffey JG, Camporota L, Esquinas AM, Grieco DL, Antonelli M, de Lima LM, Kawano-Dourado L, Maia IS, Cavalcanti AB, Clini E, Scott TE, Bates DG.   +25 more
europepmc   +1 more source

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

Advanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu, Wenhao Zhang, Yifan Zhang, Yu He, Yi Du, Yiding Zhao, Chunmeng Yao, Shengyi Sun, Xiaoyan Sheng, Qian Gao, Chao Tong, Ling Shuai   +11 more
wiley   +1 more source

Noninvasive ventilation in acute respiratory failure

Respiratory Research, 2000
Raine Richard, Martin TJ, Hovis JD, Costantino JP, Bierman MI, Donahoe MP, Rogers RM, Kreit JW, Sciurba FC, Stiller RA, Sanders MH   +10 more
doaj   +1 more source

COVID-19-Related Croup With Acute Respiratory Failure. [PDF]

Kaohsiung J Med Sci
Hsu CK, Hsieh TH, Liu YC, Chen IC.
europepmc   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

Optimising time-limited trials in acute respiratory failure: a multicentre focused ethnography protocol. [PDF]

BMJ Open
Kruser JM, Wiegmann DA, Nadig NR, Secunda KE, Hanlon BM, Moy JX, Ahmad A, Campbell EG, Donnelly HK, Martinez FJ, Polley M, Orhan C, Korth E, Stalter LN, Rowe TJ, Wu AL, Viglianti EM, Eisinger EC, Nguyen O, Halpern SD, Clapp JT.   +20 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Association between monocyte-to-lymphocyte ratio and mortality in critically ill patients with acute respiratory failure: a retrospective cohort study. [PDF]

J Thorac Dis
Xiao Z, Wang J, Liu X, Feng Z, Li J.
europepmc   +1 more source

A High‐Performance and Fully Recyclable Supramolecular Nanofibrous Membrane for Multifunctional Air Filtration

Advanced Science, EarlyView.
A green, thermoreversible self‐assembly strategy yields a multifunctional and recyclable supramolecular nanofibrous membrane. Graphene oxide (GO) nanosheet acts as a heterogeneous nucleation‐templating agent, simultaneously modulating the supramolecular crystal packing while tailoring the nanofibrous architecture for elite performance.
Wenjing Sun, Ding Yuan, Jiaqi Wan, Junyu Chen, Zhen Yan, Yinuo Yan, Senjie Dong   +6 more
wiley   +1 more source