Results 161 to 170 of about 708,169 (323)

NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2

Advanced Science, EarlyView.
The loss of NFS1 leads to its reduced binding with the transcription factor SP2, resulting in decreased expression of the downstream gene Idh2. This causes a shift in energy supply toward glycolysis in VSMCs, ultimately contributing to the occurrence and progression of AAA.
Luzheng Zhang, Yu Zhang, Dezhong Wen, Suxiang Guo, Xiaohui Qi, Heng Wang, Yujin Sun, Guangdong Yang, Yuehong Wang, Song Xue   +9 more
wiley   +1 more source

Reply to: Diaphragm excursion and diaphragm thickening fraction: commonality and conflict

European Respiratory Review
Diego Poddighe, Alexandros Kalkanis, Dries Testelmans, Greet Hermans, Daniel Langer, on behalf of all authors of “Respiratory muscle dysfunction in acute and chronic respiratory failure: how to diagnose and how to treat?”   +5 more
doaj   +1 more source

Postoperative noninvasive ventilation

Zdravniški Vestnik, 2010
Backround: Patients with acute respiratory failure often require endotracheal intubation and mechanical ventilation. Non-invasive ventilation (NIV) means ventilation without an artificial airway – endotracheal tubus or tracheostomy canulla.
Lucija Oberauner, Ludovik Strauch, Ljudmila Sakelšek-Jeras, Ana Špec-Marn, Špela Štupnik-Pirtovšek   +4 more
doaj  

Early intervention of patients at risk for acute respiratory failure and prolonged mechanical ventilation with a checklist aimed at the prevention of organ failure: protocol for a pragmatic stepped-wedged cluster trial of PROOFCheck [PDF]

, 2016
Michelle N. Gong, Liane Schenk, Ognjen Gajic, Parsa Mirhaji, Jeff A. Sloan, Yue Dong, Emir Festić, Vitaly Herasevich   +7 more
openalex   +1 more source

Sequential use of noninvasive ventilation and high flow nasal therapy after early extubation in chest trauma patients recovering from acute hypoxaemic respiratory failure

, 2022
Giuseppe Accurso, A.N. Cracchiolo, Daniela Maria Palma, Giovanni Misseri, Mariachiara Ippolito, V. Alvino, Santi Maurizio Raineri, Antonino Giarratano, Andrea Cortegiani, Cesare Gregoretti   +9 more
openalex   +1 more source

Association of Noninvasive Oxygenation Strategies With All-Cause Mortality in Adults With Acute Hypoxemic Respiratory Failure [PDF]

, 2020
Bruno L. Ferreyro, Federico Angriman, Laveena Munshi, Lorenzo Del Sorbo, Niall D. Ferguson, Bram Rochwerg, Michelle Ryu, Refik Saskin, Hannah Wunsch, Bruno R. da Costa, Damon C. Scales   +10 more
openalex   +1 more source

Transbronchial biopsies’ histopathological findings leading to successful late steroid therapy in Covid-19 acute respiratory failure [PDF]

, 2021
Francisco Klein, Juan Carlos Calderón, Melany Berdiñas Anfuso, Victoria Ruiz, María Perazzo, Hugo Paladini, Alejandra Vigliano, Juan Ossés, Pedro R. Löwenstein, Carlos Vigliano, Jorge Cáneva   +10 more
openalex   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

The effect of RAAS inhibitors on acute hypoxemic respiratory failure and in-hospital mortality in the hypertensive Covid-19 patients

, 2021
Abdurrahman Akyüz, Ferhat Işık, Burhan Aslan, Murat Çap, İlyas Kaya, Özgür Atlı, Ümit İnci, Ercan Taştan, Adem Aktan, Önder Bilge, Metin Okşul, Emre Aydın, Zülküf Karahan, Derya Deniz Altıntaş, Rojhat Altındağ, Mehmet Şahin Adıyaman, Bernas Altıntaş   +16 more
openalex   +2 more sources

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source