Results 191 to 200 of about 708,169 (323)

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

open access: yesAdvanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo   +19 more
wiley   +1 more source

Optimising time-limited trials in acute respiratory failure: a multicentre focused ethnography protocol. [PDF]

open access: yesBMJ Open
Kruser JM   +20 more
europepmc   +1 more source

High flow nasal catheter therapy versus non-invasive positive pressure ventilation in acute respiratory failure (RENOVATE trial): protocol and statistical analysis plan

open access: bronze, 2022
Israel Silva Maia   +17 more
openalex   +2 more sources

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

open access: yesAdvanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang   +9 more
wiley   +1 more source

Noninvasive respiratory supports for acute hypoxemic respiratory failure

open access: yesJournal of Intensive Medicine
Arnaud W. Thille, Rémi Coudroy
doaj   +1 more source

Dynamic chest radiography for wheezing-associated acute respiratory failure: 4 case reports. [PDF]

open access: yesRadiol Case Rep
Miyatake H   +6 more
europepmc   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

open access: yesAdvanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet   +5 more
wiley   +1 more source

COVID-19-Related Croup With Acute Respiratory Failure. [PDF]

open access: yesKaohsiung J Med Sci
Hsu CK, Hsieh TH, Liu YC, Chen IC.
europepmc   +1 more source

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