Results 101 to 110 of about 486,348 (304)

VIRAL ETIOLOGY OF ACUTE RESPIRATORY INFECTIONS IN PEDIATRIC PATIENTS IN LEBANON

Mediterranean Journal of Hematology and Infectious Diseases, 2019
 Background: Acute respiratory infections (ARI) are the leading cause of death worldwide especially among children. The majority of these infections in children are of viral etiology. In this study, we evaluated the incidence of viral ARI among children in Lebanon.
Masoud, Khaldoun, Hanna-Wakim, Rima, Zaraket, Hassan, Kharroubi, Samer, Araj, George F, Matar, Ghassan M, Dbaibo, Ghassan   +6 more
openaire   +4 more sources

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source

CHARACTERISTICS OF THE EPIDEMICAL PROCESS OF ACUTE RESPIRATORY INFECTIONS IN THE REPUBLIC OF KARELIA IN THE MODERN PERIOD

Журнал инфектологии, 2018
Acute respiratory viral infections remain the most common group of diseases causing significant social and economic damage to society. Objective: to study the epidemiological characteristics of respiratory disease influenza and other etiology in the ...
L. V. Rubis
doaj   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Rapid Multiplex Testing for Upper Respiratory Pathogens in the Emergency Department: A Randomized Controlled Trial. [PDF]

, 2019
Background:Acute upper respiratory tract infections are a common cause of emergency department (ED) visits and often result in unnecessary antibiotic treatment.
Bang, Heejung, Hon, Simson, May, Larissa, Mooso, Benjamin, Polage, Christopher, Poltavskiy, Eduard, Tatro, Grant   +6 more
core  

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Impact of SARS-CoV-2 viral load on restrictive spirometry patterns in mild COVID-19 recovered middle-aged individuals: a six-month prospective study

BMC Infectious Diseases
Background Long term respiratory complications of Corona Virus Disease-2019 (COVID-19) are of great concern. Many studies have reported altered respiratory patterns in COVID-19 recovered individuals and most of them were from severe to critically ill ...
Uzair Abbas, Ishfaque Ahmed, Saba Afshan, Zulfiqar Haider Jogezai, Parshad Kumar, Aiman Ahsan, Fatima Rehan, Niaz Hussain, Samar Faheem, Israr Ahmed Baloch, Maliha Yameen   +10 more
doaj   +1 more source

[Pharmacotherapy of acute respiratory viral infections].

Terapevticheskii arkhiv, 2013
The paper deals with the etiology, diagnosis, and treatment of acute respiratory viral infections (ARVI). It considers the currently available methods of etiotropic treatment and the tactics of antiviral therapy. Taking into consideration the fact that ARVI treatment is so far a considerable challenge associated with both the unreasonably widespread ...
openaire   +2 more sources

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Cranial neuropathy during severe acute respiratory syndrome coronavirus 2 infection: a case report

Journal of Medical Case Reports
Background Cranial neuropathy has been reported in association with coronavirus disease 2019. Multiple reports have highlighted the possibility of Miller Fisher syndrome as a delayed immune-mediated response to severe acute respiratory syndrome ...
Roya Yazdani, Farzaneh Barzkar, Zahra Mirzaasgari   +2 more
doaj   +1 more source