Results 111 to 120 of about 486,348 (304)

Epidemiology and clinical characteristics of metapneumovirus infection in hospitalized children in Novosibirsk in 2019–2024

Инфекция и иммунитет
Introduction. Metapneumovirus frequently causes respiratory tract infections in children worldwide, with clinical manifestations ranging from mild upper respiratory tract disease to severe bronchiolitis and pneumonia.
O. G. Kurskaya, A. R. Nokhova, Tereza A. Saroyan, M. V. Solomatina, E. A. Kazachkova, T. A. Gutova, Anjelika V. Anoshina, Olga A. Simkina, K. A. Sharshov, A. M. Shestopalov   +9 more
doaj   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Improvement of prophylax and treatment of acute respiratory viral infections [PDF]

Саратовский научно-медицинский журнал, 2013
The aim of the study is to estimate prophylactic and clinical efficacy of cycloferon concerning acute respiratory viral infection among military men in the period of formation of military units. Material and methods.
Yershov F.I., Shuldyakov A.A., Romantzov M.G., Ramazanova K.Kh., Shuldyakova O.G.   +4 more
doaj  

Stress significantly increases mortality following a secondary bacterial respiratory infection

Veterinary Research, 2012
A variety of mechanisms contribute to the viral-bacterial synergy which results in fatal secondary bacterial respiratory infections. Epidemiological investigations have implicated physical and psychological stressors as factors contributing to the ...
Hodgson Paul D, Aich Palok, Stookey Joseph, Popowych Yurij, Potter Andrew, Babiuk Lorne, Griebel Philip J   +6 more
doaj   +1 more source

The Role of Genetic Factors in the Development of Acute Respiratory Viral Infection COVID-19: Predicting Severe Course and Outcomes. [PDF]

Biomedicines, 2022
Minashkin MM, Grigortsevich NY, Kamaeva AS, Barzanova VV, Traspov AA, Godkov MA, Ageev FA, Petrikov SS, Pozdnyakova NV.   +8 more
europepmc   +1 more source

KCNJ2 is Required for NLRP3 Inflammasome Activation That Drives Allergic Airway Inflammation and Remodeling

Advanced Science, EarlyView.
This study aims to evaluate the impact of the potassium channel KCNJ2 on asthma development. KCNJ2 promotes NLRP3 inflammasome activation through both Ca2+ influx and K+ efflux in airway epithelial cells, which drives allergic airway inflammation and remodeling, suggesting a promising therapeutic target for asthma.
Yachao Cui, Shumei Wu, Yang Peng, Yiqi Liu, Li Che, Shiying Chen, Feng Zhang, Dajiang Qin, Shiyue Li, Pixin Ran, Wenguang Yin   +10 more
wiley   +1 more source

A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat

Advanced Science, EarlyView.
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su, Haosen Yang, Xiaokai Li, Tingting Jiang, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Yan Wang, Li Li, Hongping Zhang, Linjie Wang   +10 more
wiley   +1 more source

Viral Infection Related to The Appearance of Acute Bacterial Respiratory Tract Infections

Journal of the Japanese Association for Infectious Diseases, 2000
To investigate what viruses are related to acute bacterial respiratory tract infections, we prospectively evaluated 113 cases with respiratory tract infections (always accompanying by purulent sputum) experienced between July 1998 and March 2000. Acute viral infections were detected in 25 cases (22%); 10 cases of influenza A virus and 6 cases of ...
Y, Kobashi, T, Sunagawa, N, Asaoka, H, Ohba, H, Yoneyama, N, Okimoto, R, Soejima   +6 more
openaire   +3 more sources

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Optimization of the therapy of ARVI and influenza in outpatient practice

Лечащий Врач
Background. Acute respiratory viral infections are a pathology that most often occurs in outpatient therapeutic practice (about 40 million cases per year). The term acute respiratory viral infection is a collective concept and denotes a group of diseases
D. S. Sukhanov, V. V. Basina, Yu. S. Alekseeva, E. V. Timofeev   +3 more
doaj   +1 more source