Results 101 to 110 of about 51,985 (253)
Infection control in the brain and the eye
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source
Bilateral acute retinal necrosis-A case report
A 42 year old man presented with acute bilateral uveitis and necrotizing retinitis. Systemic investigations including test for AIDS and CMV retinitis were negative.
Prasad Palimar, Upadhyaya N
doaj
Immunopathology of Virus-Induced Anterior Uveitis [PDF]
Herpes simplex virus, varicella zoster virus, human cytomegalovirus, and rubella virus are the most common causes of virus-induced anterior uveitis.
Chan, A.S.Y. (Anita S. Y.) +3 more
core +2 more sources
Circulating angiogenesis‐related biomarkers in sickle cell retinopathy and maculopathy
Summary Sickle cell disease (SCD), encompassing genotypes such as HbSS and HbSC, leads to retinal complications such as sickle cell retinopathy (SCR) and maculopathy (SCM) through poorly understood mechanisms. This study explored associations of a panel of circulating angiogenesis‐related factors with SCR and SCM.
Rajani P. Brandsen +6 more
wiley +1 more source
Purpose: To report the unique clinical findings of a case of Herpes Simplex Virus Type 2 herpetic retinitis manifesting as a large elevated subretinal lesion.
Daniel Wang +4 more
doaj +1 more source
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
Antiviral selection in the management of acute retinal necrosis
Patrick MK Tam1, Claire Y Hooper2, Susan Lightman21Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, N.T., Hong Kong, People’s Republic of China; 2Institute of Ophthalmology ...
Patrick MK Tam +2 more
doaj
Timing of Prophylactic and Early Vitrectomy for First-Presenting or Recurrent Acute Retinal Necrosis Syndrome [PDF]
Acute retinal necrosis syndrome (ARNS) is a herpetic infectious eye disease that presents clinicians with difficult decisions to make about the indication and timing of surgical intervention.
Matsuo, Toshihiko
core +1 more source
Intraocular Metastasis: Differential Diagnosis and Management
ABSTRACT Intraocular metastases represent the most common type of malignant intraocular tumour in adults. These commonly affect the choroid but can also involve the iris, ciliary body, retina, vitreous, optic disc or lens. Breast and lung cancer are the most common origins of intraocular metastases.
Genovefa Μachairoudia +3 more
wiley +1 more source
Autoimmunity, Autoinflammation, and Infection in Uveitis [PDF]
Funding/Support: No funding or grant support. Financial Disclosures: John V. Forrester has received an honorarium for lecturing from Janssen (London, UK). Lucia Kuffova has undertaken consultancy work for Abbvie (London, UK). Andrew D.
Dick, Andrew D. +2 more
core +4 more sources

