Results 41 to 50 of about 35,095 (251)
Graphical abstract MP3‐pulses‐COVID‐19 trial. Abstract Background The efficacy and safety of high versus medium doses of glucocorticoids for the treatment of patients with COVID‐19 has shown mixed outcomes in controlled trials and observational studies.
Luis Corral‐Gudino+21 more
wiley +1 more source
Antibiotics for the primary prevention of acute rheumatic fever: a meta-analysis
Background Rheumatic fever continues to put a significant burden on the health of low socio-economic populations in low and middle-income countries despite the near disappearance of the disease in the developed world over the past century.
Volmink Jimmy A+2 more
doaj +1 more source
Abstract Background and purpose Clinical outcome information on patients with neuromuscular diseases (NMDs) who have been infected with SARS‐CoV‐2 is limited. The aim of this study was to determine factors associated with the severity of COVID‐19 outcomes in people with NMDs.
Chiara Pizzamiglio+93 more
wiley +1 more source
Diagnosis of acute rheumatic fever
Diagnosis of acute rheumatic fever.
B. S. Belov+10 more
doaj +1 more source
Explainable Deep Learning Algorithm for Distinguishing Incomplete Kawasaki Disease by Coronary Artery Lesions on Echocardiographic Imaging [PDF]
Background and Objective: Incomplete Kawasaki disease (KD) has often been misdiagnosed due to a lack of the clinical manifestations of classic KD. However, it is associated with a markedly higher prevalence of coronary artery lesions. Identifying coronary artery lesions by echocardiography is important for the timely diagnosis of and favorable outcomes
arxiv
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai+6 more
wiley +1 more source
ABSTRACT Hereditary multiple osteochondromas (HMO) is an autosomal dominant disorder caused by heterozygous deleterious variants in the EXT1 or EXT2 genes. While the clinical core phenotype is well established and mainly consists of bone deformities, limb length discrepancies, multiple benign bone neoplasms, and increased risk of chondrosarcoma, the ...
Francesco Comisi+7 more
wiley +1 more source
Application of humanized mice in the safety experiments of antibody drugs
The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun+9 more
wiley +1 more source
Background Acquired complete heart block, in pediatric age is mainly the results of direct injury to conduction tissue during cardiac surgery or cardiac catheterisation.
Carano Nicola+5 more
doaj +1 more source
Sydenham's chorea (SC) is the neurological manifestation associated with acute rheumatic fever (ARF), triggered by a group A streptococcal (GAS) infection. Anti‐GAS antibodies cross‐reacting with tissue proteins are implicated in the development of neurological changes. In this study, using an animal model, we demonstrate that a compromised blood–brain
Rukshan Ahamed Mohamed Rafeek+8 more
wiley +1 more source