Results 11 to 20 of about 507,051 (317)

Statistical analysis of the primary outcome in acute stroke trials [PDF]

, 2012
Common outcome scales in acute stroke trials are ordered categorical or pseudocontinuous in structure but most have been analyzed as binary measures. The use of fixed dichotomous analysis of ordered categorical outcomes after stroke (such as the modified
Lees, K.R., Saver, J.L., Howard, G., TONI, Danilo, Altman, H., Schellinger, P.D., Bland, M., Hogg, C., Bath, P.M.W., European Stroke Organisation Outcomes Working Group   +9 more
core   +1 more source

Time-to-care metrics in patients with interhospital transfer for mechanical thrombectomy in north-east Germany: Primary telestroke centers in rural areas vs. primary stroke centers in a metropolitan area

Frontiers in Neurology, 2023
BackgroundMechanical thrombectomy (MT) is highly effective in large vessel occlusion (LVO) stroke. In north-east Germany, many rural hospitals do not have continuous neurological expertise onsite and secondary transport to MT capable comprehensive stroke
Christoph Riegler, Christoph Riegler, Janina R. Behrens, Janina R. Behrens, Janina R. Behrens, Janina R. Behrens, Claudia Gorski, Claudia Gorski, Claudia Gorski, Anselm Angermaier, Anselm Angermaier, Stephan Kinze, Stephan Kinze, Stephan Kinze, Ramanan Ganeshan, Ramanan Ganeshan, Ramanan Ganeshan, Andrea Rocco, Alexander Kunz, Alexander Kunz, Alexander Kunz, Tobias J. Müller, Andreas Bitsch, Albert Grüger, Joachim E. Weber, Joachim E. Weber, Joachim E. Weber, Joachim E. Weber, Eberhard Siebert, Eberhard Siebert, Kerstin Bollweg, Kerstin Bollweg, Regina von Rennenberg, Regina von Rennenberg, Heinrich J. Audebert, Heinrich J. Audebert, Heinrich J. Audebert, Christian H. Nolte, Christian H. Nolte, Christian H. Nolte, Christian H. Nolte, Hebun Erdur, Hebun Erdur, Hebun Erdur   +43 more
doaj   +1 more source

Diagnostic and prognostic utility of brain collaterals in acute ischaemic stroke: Current knowledge and insights on treatment decision-making [PDF]

Romanian Journal of Neurology, 2021
Stroke is a leading cause of death and disability worldwide. The advent of acute reperfusion therapy, intravenous thrombolysis and endovascular thrombectomy, has revolutionised the field of stroke medicine, and neurology in general.
Akansha Sinha, Miriam Priglinger-Coorey, Peter Stanwell, Negman Alvarado, Murray Killingsworth, Sonu Menachem Maimonides Bhaskar   +5 more
doaj   +1 more source

Antioxidant status in acute stroke patients and patients at stroke risk [PDF]

, 2004
Background and Purpose: Antioxidant enzymes like copper/ zinc superoxide dismutase (SOD), catalase and gluthatione peroxidase (GSHPx) are part of intracellular protection mechanisms to overcome oxidative stress and are known to be activated in vascular ...
Haberl, R. L., Winnefeld, K., S. Streck, Roskos, M., M. Roskos, R.L. Haberl, K. Winnefeld, Zimmermann, C., Streck, S., C. Zimmermann   +9 more
core   +1 more source

Contemporary outcome measures in acute stroke research: choice of primary outcome measure [PDF]

, 2012
BACKGROUND AND PURPOSE: The diversity of available outcome measures for acute stroke trials is challenging and implies that the scales may be imperfect.
D. m. Kerr, R. Fulton, Matchar, D., D. Matchar, K. r. Lees, Schellinger, P., Bath, P.M.W., P. m. w. Bath, Lees, K.R., Kerr, D.M., Toni, D., TONI, Danilo, Sehra, R., R. Sehra, Hacke, W., P. d. Schellinger, Fulton, R., W. Hacke   +17 more
core   +1 more source

A Systematic Review of the Causes and Management of Nonthrombotic Embolic Stroke of Tissue Origin

Stroke Research and Treatment, 2018
Introduction. Various bodily tissues have been reported to enter the arterial circulation and embolize to the brain resulting in ischemic stroke.
Sarah Mello, Ciaran Judge, Roisin Kelly, David Bradley, Joseph Harbison   +4 more
doaj   +1 more source

Safety of intravenous thrombolysis for acute ischemic stroke in patients receiving antiplatelet therapy at stroke onset [PDF]

, 2010
<p><b>Background and Purpose:</b> Antiplatelets (APs) may increase the risk of symptomatic intracerebral hemorrhage (ICH) following intravenous thrombolysis after ischemic stroke.</p> <p><b>Methods:</b> We ...
Wahlgren, N., Luijckx, G-J, Sykora, M., Wahlgren, N,, Diedler, J., Diedler, Jennifer, Overgaard, Karsten, Overgaard, K., Diedler, J, Ringleb, Peter, Uyttenboogaart, M., Ford, G.A., Soinne, Lauri, Overgaard, K, Lees, K.R., Lees, KR, Sykora, M, Uyttenboogaart, M, Uyttenboogaart, Maarten, Ringleb, P., Ahmed, Niaz, Luijckx, G.J., Luijckx, Gert-Jan, Ahmed, N,, Ahmed, N., Lees, Kennedy R., Wahlgren, Nils, Ford, GA, Soinne, L, Soinne, L., Sykora, Marek, Ford, Gary A., Uyttenboogaart, Maarten; id_orcid   +32 more
core   +1 more source

Effect of hyperthermia on prognosis after acute ischemic stroke [PDF]

, 2009
<p><b>Background and Purpose:</b> Experimental studies have shown that hyperthermia is a determinant of poor outcome after ischemic stroke.
Lees, K.R., Shuaib, A., Saqqur, M., Saini, M., Kamruzzaman, A.   +4 more
core   +1 more source

Ankle contracture in people with acquired brain injury (ABI), intervention, and outcome following inpatient neurorehabilitation categorized by severity

The Journal of the International Society of Physical and Rehabilitation Medicine, 2023
Background:. Acquired brain injury frequently causes difficulty with moving and walking, which if not actively managed, can lead to secondary contracture and deformity. Intervention to manage ankle contracture may include conservative methods (eg, serial
Stephen Ashford, PhD, MSc, BSc, Charlotte Elsmore, BSc, Aideen Steed, BSc, Alexia Diggins, BSc, Alice Walden-Smith, BSc, Heather Williams, MSc   +5 more
doaj   +1 more source

Bolus-Infusion Delays of Alteplase during Thrombolysis in Acute Ischaemic Stroke and Functional Outcome at 3 Months

Stroke Research and Treatment, 2014
Background. The efficacy of alteplase in acute ischaemic stroke (AIS) is highly time dependent. Hence, alteplase is administered as soon as possible with a bolus followed by an infusion.
Paul Acheampong, Margaret T. May, Gary A. Ford, Anand K. Dixit   +3 more
doaj   +1 more source