Results 41 to 50 of about 507,051 (317)

A multicentre observational study of presentation and early assessment of acute stroke

, 2002
Objective To investigate delays in the presentation to hospital and evaluation of patients with suspected stroke.Design Multicentre prospective observational study.Setting 22 hospitals in the United Kingdom and Dublin.Participants 739 patients with ...
Kalra, L, Vass, RI, Brown, M M, ?, ?, Harraf, F, Lees, KR, Lees, K R, Acute Stroke Intervention Study Gr, Sharma, A K, Sharma, AK, Vass, R I, Brown, MM   +11 more
core   +1 more source

Insular cortex hypoperfusion and acute phase blood glucose after stroke: a CT perfusion study [PDF]

, 2007
<p><b>Background and Purpose:</b> Insular cortex ischemia is proposed to mediate a sympathetic stimulus that leads to acute hyperglycemia after stroke.</p> <p><b>Methods:</b> We retrospectively analyzed ...
Muir, K.W., McCormick, M., Moreton, F.C.
core   +1 more source

Acute Stroke Care in Mexico City: The Hospital Phase of a Stroke Surveillance Study

Brain Sciences, 2022
Background: Acute stroke care has greatly improved in recent decades. However, the increasing stroke mortality in low-to-middle income countries suggests that progress has not been reached completely by these populations.
Emmanuel Aguilar-Salas, Guadalupe Rodríguez-Aquino, Katya García-Domínguez, Catalina Garfias-Guzmán, Erika Hernández-Camarillo, Nayeli Oropeza-Bustos, Rubí Arguelles-Castro, Ameyalli Mitre-Salazar, Gloria García-Torres, Marco Reynoso-Marenco, Eduardo Morales-Andrade, Luis Gervacio-Blanco, Víctor García-López, Gabriel Valiente-Herves, Manuel Martínez-Marino, Fernando Flores-Silva, Erwin Chiquete, Carlos Cantú-Brito   +17 more
doaj   +1 more source

Early recurrent ischemic stroke complicating intravenous thrombolysis for stroke: incidence and association with atrial fibrillation [PDF]

, 2010
<p><b>Background and Purpose:</b> Mechanisms of early neurologic deterioration after treatment with intravenous, recombinant, tissue-type plasminogen activator (IV rt-PA) include symptomatic intracerebral hemorrhage (SICH) and early ...
Tracey Baird, Teasdale, E., Mostafa Awadh, Evelyn Teasdale, Muir, K.W., Santosh, C., Keith W. Muir, Baird, T., MacDougall, N., Celestine Santosh, Niall MacDougall, Awadh, M.   +11 more
core   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

The Virtual International Stroke Trials Archive [PDF]

, 2007
Background and Purpose - Stroke has global importance and it causes an increasing amount of human suffering and economic burden, but its management is far from optimal.
Donnan, Geoffrey A., Kaste, M., HENNERICI, Michael G, Teal, P., Gregson, B.A., Hacke, Werner, Marler, J.R., Marler, John R., Fisher, M., GREGSON, Barbara A, Wahlgren, Nils-Gunnar, Curram, John, Grotta, J., MARLER, John R, Davis, Stephen M., Sacco, Ralph L., Donnan, G.A., Myzoon, Ali, Bath, Philip M.W., Teal, Philip, WEIR, Christopher J, Weir, C.J., Gregson, Barbara A., Fisher, Marc, Hommel, Marc, Hacke, W., BATH, Philip M. W, Sacco, R.L., Diener, Hans-Christoph, Warach, S., DONNAN, Geoffrey A, Hennerici, Michael G., Wahlgren, N.-G., Lees, K.R., Grotta, James, Hennerici, M.G., Kaste, Markku, Weir, Christopher J., Warach, Steven, Lees, Kennedy R., DAVIS, Stephen M, Bath, P.M.W., Ali, M., Curram, J., Diener, H.-C., Ali, Myzoon, Davis, S.M., SACCO, Ralph L, Hommel, M., LEES, Kennedy R   +49 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Post‐recanalization administration of rapamycin improves functional outcome and reduces infarct size in a rat model of ischemic stroke

Neuroprotection
Aim Despite advances in endovascular recanalization for ischemic stroke, many patients experience poor outcomes. Adjunct cerebroprotective therapies are needed to improve recovery.
Anna M. Schneider, Yvonne Couch, James Larkin, Alastair M. Buchan, Daniel J. Beard   +4 more
doaj   +1 more source

Country-Wide Analysis of Systemic Factors Associated With Acute Ischemic Stroke Door to Needle Time

Frontiers in Neurology, 2019
Objective: Pre-hospital, in-hospital, and patient factors are associated with variation in door to needle (DTN) time in acute ischemic stroke (AIS).
Ferghal McVerry, Annemarie Hunter, Kevin Dynan, Maureen Matthews, Michael McCormick, Ivan Wiggam, Djamil Vahidassr, Fintan McErlean, Mike Stevenson, Emer Hopkins, Jacqueline McKee, James Kelly, Fiona Kennedy, Mark O. McCarron   +13 more
doaj   +1 more source

Association between disability measures and healthcare costs after initial treatment for acute stroke [PDF]

, 2007
<p><b>Background and Purpose:</b> The distribution of 3-month modified Rankin scale (mRS) scores has been used as an outcome measure in acute stroke trials.
Chang, T.P., Walters, M.R., Walters, Matthew R., Dawson, J., Davis, Stephen M., Lees, Kennedy R., Diener, Hans-Christoph, Ali, M., Lees, J.S., Lees, K.R., Chang, Tou-Pin, Ali, Myzoon, Diener, H.C., Davis, S.M., Dawson, Jesse, Lees, Jennifer S.   +15 more
core   +1 more source