Results 41 to 50 of about 2,899,122 (265)

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Country-Wide Analysis of Systemic Factors Associated With Acute Ischemic Stroke Door to Needle Time

Frontiers in Neurology, 2019
Objective: Pre-hospital, in-hospital, and patient factors are associated with variation in door to needle (DTN) time in acute ischemic stroke (AIS).
Ferghal McVerry, Annemarie Hunter, Kevin Dynan, Maureen Matthews, Michael McCormick, Ivan Wiggam, Djamil Vahidassr, Fintan McErlean, Mike Stevenson, Emer Hopkins, Jacqueline McKee, James Kelly, Fiona Kennedy, Mark O. McCarron   +13 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Dose escalation of desmoteplase for acute ischemic stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onset [PDF]

, 2006
<p><b>Background and Purpose:</b> Desmoteplase is a novel plasminogen activator with favorable features in vitro compared with available agents.
Lees, K.R., Hacke, W.l, Sachara, C., Rowley, H.A., Furlan, A.J., Al, R.Y., Eyding, D., Albers, G.W., Soehngen, M., Warach, S.   +9 more
core   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

An observational study of patient characteristics associated with the mode of admission to acute stroke services in North East, England [PDF]

, 2013
Objective Effective provision of urgent stroke care relies upon admission to hospital by emergency ambulance and may involve pre-hospital redirection.
Price, Christopher, Christopher I Price, Wood Ruth, Peter McMeekin, Duckett Jay, Gray Joanne, Gray, Joanne, Portas Karen, Portas, Karen, McMeekin, Peter, Rae Victoria, McMeekin Peter, Rae, Victoria, Gary A Ford, Wood, Ruth, Rodgers Helen, Karen Portas, Duckett, Jay, Price, Christopher I. M., Rodgers, Helen, Jay Duckett, Helen Rodgers, Ford, Gary A., Joanne Gray, Victoria Rae, Ford Gary A., Ruth Wood, Price Christopher I.   +27 more
core   +1 more source

Acute Stroke Care in Mexico City: The Hospital Phase of a Stroke Surveillance Study

Brain Sciences, 2022
Background: Acute stroke care has greatly improved in recent decades. However, the increasing stroke mortality in low-to-middle income countries suggests that progress has not been reached completely by these populations.
Emmanuel Aguilar-Salas, Guadalupe Rodríguez-Aquino, Katya García-Domínguez, Catalina Garfias-Guzmán, Erika Hernández-Camarillo, Nayeli Oropeza-Bustos, Rubí Arguelles-Castro, Ameyalli Mitre-Salazar, Gloria García-Torres, Marco Reynoso-Marenco, Eduardo Morales-Andrade, Luis Gervacio-Blanco, Víctor García-López, Gabriel Valiente-Herves, Manuel Martínez-Marino, Fernando Flores-Silva, Erwin Chiquete, Carlos Cantú-Brito   +17 more
doaj   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

Additional outcomes and subgroup analyses of NXY-059 for acute ischemic stroke in the SAINT I trial [PDF]

, 2006
<p><b>Background and Purpose:</b> NXY-059 is a free radical-trapping neuroprotectant demonstrated to reduce disability from ischemic stroke. We conducted analyses on additional end points and sensitivity analyses to confirm our findings.
Lees, K.R., Diener, H.-C., Shuaib, A., Zivin, J.A., Davis, S.M., Wasiewski, W., Lyden, P., Emeribe, U., Ashwood, T., Hardemark, H.G., Davalos, A., Grotta, J.   +11 more
core   +1 more source

Risk of Post-stroke Epilepsy Following Stroke-Associated Acute Symptomatic Seizures

Frontiers in Aging Neuroscience, 2021
Objective: Post-stroke epilepsy (PSE) is associated with increased morbidity and mortality. Stroke-associated acute symptomatic seizures are an important risk factor: 20.8–34.3% of these patients will go on to develop PSE.
Ru Lin, Yaoyao Yu, Yi Wang, Emma Foster, Patrick Kwan, Mengqi Lin, Niange Xia, Huiqin Xu, Chenglong Xie, Yunjun Yang, Xinshi Wang, Xinshi Wang   +11 more
doaj   +1 more source