Results 31 to 40 of about 4,986,959 (302)

ACUTE TOXIC CHOREA [PDF]

The Journal of Nervous and Mental Disease, 1908
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openaire   +2 more sources

Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia

Science Translational Medicine, 2014
CD19 CAR T cell therapy induces complete remissions in 88% of 16 adult patients with relapsed or refractory acute lymphoblastic leukemia. CARving Out a Niche for CAR T Cell Immunotherapy Relapsed or refractory B acute lymphoblastic leukemia (B-ALL) in ...
M. Davila, I. Rivière, Xiuyan Wang, S. Bartido, Jae H. Park, K. Curran, S. Chung, J. Stefanski, Oriana Bórquez-Ojeda, M. Olszewska, Jinrong Qu, Teresa Wasielewska, Q. He, Mitsú J. Fink, Himaly Shinglot, M. Youssif, M. Satter, Yongzeng Wang, James Hosey, Hilda Quintanilla, E. Halton, Y. Bernal, Diana C. G. Bouhassira, M. Arcila, M. Gonen, G. Roboz, P. Maslak, D. Douer, M. Frattini, S. Giralt, M. Sadelain, R. Brentjens   +31 more
semanticscholar   +1 more source

Preliminary studies of acute and sub-chronic toxicity of the aqueous extract of Guibourtia tessmannii (Harms) J. Leonard stem barks (Caesalpiniaceae) in mice and rats

Asian Pacific Journal of Tropical Biomedicine, 2016
Objective: To investigate the toxicity of aqueous extract of Guibourtia tessmannii (Harms) J. Leonard (G. tessmannii) and evaluate its safety. Methods: NMRI mice were used to determine the acute toxicity of G. tessmannii. Increasing concentrations of the
Noreen Orianna Koumba Madingou, Aristide Traore, Alain Souza, Marlaine Michelle Boukandou Mounanga, Raissa Reine Aworet Samseny, Sylvin Ouedraogo, Alfred Sababenedyo Traore   +6 more
doaj   +1 more source

Size-dependent acute toxicity of silver nanoparticles in mice

Journal of Toxicologic Pathology, 2017
In this study, we aimed to evaluate changes in the acute toxicity of intraperitoneally administered silver nanoparticles (AgNPs) of varying sizes in BALB/c mice. Seven-week-old female BALB/c mice were intraperitoneally administered AgNPs measuring 10, 60,
Young-Man Cho, Y. Mizuta, Jun-ichi Akagi, T. Toyoda, Mizuki Sone, K. Ogawa   +5 more
semanticscholar   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Safety assessment of AYUSH-64 through acute and 90-days repeated dose oral toxicity

International Journal of Ayurveda Research, 2023
Background: AYUSH-64 is a polyherbal Ayurvedic antimalarial formulation, also found effective in COVID-19. Aim: The present study was designed to investigate the safety of AYUSH-64 in acute and 90-day repeated dose oral toxicity as per the Organization ...
Srikanth Ala, Sudesh N. Gaidhani, S. Viswanth Reddy, YR Sanjaya Kumar, Shrirang B. Jamadagni   +4 more
doaj   +1 more source

The Toxicity, Pathophysiology, and Treatment of Acute Hydrazine Propellant Exposure: A Systematic Review.

Military Medicine, 2020
INTRODUCTION Hydrazines are highly toxic inorganic liquids that are used as propellants in military and aviation industries, such as the U.S. Air Force F-16 Emergency Power Unit and SpaceX SuperDraco Rockets.
HoanVu Nguyen, J. Chenoweth, V. Bebarta, T. Albertson, C. Nowadly   +4 more
semanticscholar   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

ProTox 3.0: a webserver for the prediction of toxicity of chemicals

Nucleic Acids Research
Interaction with chemicals, present in drugs, food, environments, and consumer goods, is an integral part of our everyday life. However, depending on the amount and duration, such interactions can also result in adverse effects.
Priyanka Banerjee, Emanuel Kemmler, Mathias Dunkel, R. Preissner   +3 more
semanticscholar   +1 more source

Galleria mellonella (greater wax moth) larvae as a model for antibiotic susceptibility testing and acute toxicity trials

BMC Research Notes, 2017
BackgroundInfectivity trials and toxicity testing in rodents are important prerequisites to the use of compounds in man. However, trials in rats and mice are expensive and there are ethical considerations.
K. Ignasiak, A. Maxwell
semanticscholar   +1 more source