Results 61 to 70 of about 4,986,959 (302)

Safety of AYUSH OSTO in experimental animals

International Journal of Ayurveda Research
Background: AYUSH OSTO is a coded formulation developed by the Central Council for Research in Ayurvedic Sciences for the treatment of bone-related disorders. Aim: The present study focused on evaluating the safety of AYUSH OSTO through acute, 28-day sub-
Sudesh N. Gaidhani, M. M. Padhi, Arjun Singh, Viswanth Reddy, Srikanth Ala   +4 more
doaj   +1 more source

Unraveling the safety of adjuvant radiotherapy in prostate cancer: impact of older age and hypofractionated regimens on acute and late toxicity - a multicenter comprehensive analysis

Frontiers in Oncology, 2023
BackgroundThe objective of this study was to assess the impact of age and other patient and treatment characteristics on toxicity in prostate cancer patients receiving adjuvant radiotherapy (RT).Materials and methodsThis observational study (ICAROS-1 ...
Milly Buwenge, Gabriella Macchia, Letizia Cavallini, Letizia Cavallini, Annalisa Cortesi, Claudio Malizia, Lorenzo Bianchi, Lorenzo Bianchi, Maria Ntreta, Alessandra Arcelli, Ilaria Capocaccia, Ilaria Capocaccia, Elena Natoli, Elena Natoli, Savino Cilla, Francesco Cellini, Francesco Cellini, Luca Tagliaferri, Lidia Strigari, Silvia Cammelli, Silvia Cammelli, Riccardo Schiavina, Riccardo Schiavina, Eugenio Brunocilla, Eugenio Brunocilla, Alessio Giuseppe Morganti, Alessio Giuseppe Morganti, Francesco Deodato, Francesco Deodato   +28 more
doaj   +1 more source

ASBMT Consensus Grading for Cytokine Release Syndrome and Neurological Toxicity Associated with Immune Effector Cells

Biology of Blood and Marrow Transplantation, 2018
Chimeric antigen receptor (CAR) T cell therapy is rapidly emerging as one of the most promising therapies for hematological malignancies. Two CAR T products were recently approved in the United States and Europe for the treatment of patients with ...
Daniel W. Lee, B. Santomasso, F. Locke, A. Ghobadi, C. Turtle, Jennifer N. Brudno, M. Maus, Jae H. Park, E. Mead, S. Pavletic, W. Go, L. Eldjerou, R. Gardner, N. Frey, K. Curran, K. Peggs, M. Pasquini, J. Dipersio, Marcel R. M. van den Brink, K. Komanduri, S. Grupp, S. Neelapu   +21 more
semanticscholar   +1 more source

Bridging the Gap in Neuroblastoma Care: Consensus‐Based Statements With Recommendations for Improved Patient and Caregiver Experiences

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma's complex, heterogeneous biology poses significant diagnostic and therapeutic challenges, often requiring caregivers to absorb complex information and participate in time‐sensitive decisions. However, caregivers often feel unprepared to evaluate options.
Vickie Buenger, Joseph Bauer, Jennifer Diamond, Maggie Fader, Shae Hansen, Jacqueline M. Kraveka, Johanna Schoen, Amber Shearer, Dena Sherwood   +8 more
wiley   +1 more source

Phytochemistry and toxicological assessment of Bryonia dioica roots used in north-African alternative medicine

Open Chemistry, 2019
To investigate the phytochemical composition, acute and sub-acute toxicity of the aqueous extract of B. dioica roots. The phytochemical analysis was performed using gas chromatography-mass spectrometry (GC-MS).
Bourhia Mohammed, Bari Ahmed, Ali Syed Saeed, Benbacer Laila, khlil Naima   +4 more
doaj   +1 more source

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Acute and late toxicity in prostate cancer patients treated by dose escalated intensity modulated radiation therapy and organ tracking

Radiation Oncology, 2008
Background To report acute and late toxicity in prostate cancer patients treated by dose escalated intensity-modulated radiation therapy (IMRT) and organ tracking.
Behrensmeier Frank, Madlung Axel, Tille Jan, Bigler Roland, Manser Peter, Vetterli Daniel, Vock Jacqueline, Ghadjar Pirus, Mini Roberto, Aebersold Daniel M   +9 more
doaj   +1 more source

Toxicological profile of the aqueous-fermented extract of Musa paradisiaca in rats [PDF]

Avicenna Journal of Phytomedicine, 2018
Objective: This study was conducted to assess the toxicity profile of the aqueous-fermented extract of Musa paradisiaca in rats. Materials and Methods: In acute toxicity test, the rats of different groups were orally administered with a single dose of ...
Eziuche Ugbogu, Victor Chibueze Ude, Iheanyichukwu Elekwa, Uche Arunsi, Chikezie Uche-Ikonne, Chinedu Nwakanma   +5 more
doaj   +1 more source

Mechanisms of Acute Cocaine Toxicity [PDF]

The Open Pharmacology Journal, 2008
Patients with acute cocaine poisoning present with life-threatening symptoms involving several organ systems. While the effects of cocaine are myriad, they are the result of a limited number of cocaine-protein interactions, including monoamine transporter, neurotransmitter receptor and voltage-gated ion channels.
Kennon, Heard, Robert, Palmer, Nancy R, Zahniser   +2 more
openaire   +2 more sources