Results 71 to 80 of about 795,614 (304)

Unraveling the safety of adjuvant radiotherapy in prostate cancer: impact of older age and hypofractionated regimens on acute and late toxicity - a multicenter comprehensive analysis

Frontiers in Oncology, 2023
BackgroundThe objective of this study was to assess the impact of age and other patient and treatment characteristics on toxicity in prostate cancer patients receiving adjuvant radiotherapy (RT).Materials and methodsThis observational study (ICAROS-1 ...
Milly Buwenge, Gabriella Macchia, Letizia Cavallini, Letizia Cavallini, Annalisa Cortesi, Claudio Malizia, Lorenzo Bianchi, Lorenzo Bianchi, Maria Ntreta, Alessandra Arcelli, Ilaria Capocaccia, Ilaria Capocaccia, Elena Natoli, Elena Natoli, Savino Cilla, Francesco Cellini, Francesco Cellini, Luca Tagliaferri, Lidia Strigari, Silvia Cammelli, Silvia Cammelli, Riccardo Schiavina, Riccardo Schiavina, Eugenio Brunocilla, Eugenio Brunocilla, Alessio Giuseppe Morganti, Alessio Giuseppe Morganti, Francesco Deodato, Francesco Deodato   +28 more
doaj   +1 more source

The acute toxicity of ephedrine.

Experimental Biology and Medicine, 1925
In our preliminary report,1, 2 mention was made concerning the toxicity of ephedrine in rats and rabbits. As the drug is possibly of clinical importance in the treatment of asthma and hypotension as demonstrated in the Peking Union Medical College Hospital, it is thought desirable to study its toxicity more in detail.Ephedrine sulphate was used in all ...
openaire   +1 more source

Acute Toxicity Evaluation of Impatiens Balsamina Linn. Stem and Leaf N-hexane Fraction Using Oecd 425 Guideline [PDF]

, 2014
Garden balsam (Impatiens balsamina Linn) is a plant that has been used for joint pain, insect bite, promotes regular menstrual cycle and prevents stomach cancer.
Kusharyanti, I. (Indri), Nurbaeti, S. N. (Siti), Sunggono, B. W. (Benny)   +2 more
core  

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

Acute, sub-acute and developmental toxicity studies of molybdenum disulfide nanoflowers in rats, as per OECD guidelines

BMC Pharmacology and Toxicology
Background This study aimed to investigate the potential toxic effects of Molybdenum disulfide nano-flowers (MoS2 NF), which have been suggested as a chemotherapeutic agent, but lack previous toxicity studies.
Farina Hanif, Aslam Khan, Fareeha Anwar, Haseeb ullah, Muhammad Furqan Akhtar, Muhammad Imran Khan   +5 more
doaj   +1 more source

Acute toxicity of atrazine to Oreochromis niloticus fingerlings [PDF]

, 2001
Acute toxicity of atrazine to Oreochromis niloticus was undertaken to find the lethal concentration (LC) 50 of atrazine using fingerlings. Different concentrations were prepared in mg/L.
Jiya, K.R., Majinga, S.I.I., Mbagwu, L.C.   +2 more
core  

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Phytochemistry and toxicological assessment of Bryonia dioica roots used in north-African alternative medicine

Open Chemistry, 2019
To investigate the phytochemical composition, acute and sub-acute toxicity of the aqueous extract of B. dioica roots. The phytochemical analysis was performed using gas chromatography-mass spectrometry (GC-MS).
Bourhia Mohammed, Bari Ahmed, Ali Syed Saeed, Benbacer Laila, khlil Naima   +4 more
doaj   +1 more source

Acute and sub-acute toxicity of aqueous extract of aerial parts of Caralluma dalzielii N. E. Brown in mice and rats

Heliyon, 2019
Caralluma dalzielii N. E. Brown (Asclepiadaceae) is a cactus-like shaped shrub widely used in traditional medicine for the treatment of rheumatoid arthritis, diabetes, infertility and impotence.
Chinenye Jane Ugwah-Oguejiofor, Charles Ogbonna Okoli, Michael Oguejiofor Ugwah, Millicent Ladi Umaru, Chiedozie Smart Ogbulie, Halilu Emmanuel Mshelia, Mohammed Umar, Anoka Ayembe Njan   +7 more
doaj   +1 more source

Acute and repeated dose 60-day oral toxicity assessment of chemically characterized Berberis hispanica Boiss. and Reut in Wistar rats

Open Chemistry, 2021
Berberis hispanica Boiss. & Reut (B. hispanica) belongs to the family Berberidaceae, which is currently used in traditional medicines. This article aimed to study the phytochemical composition and acute and subacute toxicity of B.
El Fakir Loubna, Bourhia Mohammed, Salamatullah Ahmad Mohammad, Alzahrani Abdulhakeem, Ullah Riaz, Ezzeldin Essam, Mostafa Gamal A., Bari Ahmed, Alaoui Tajelmolk, Gmouh Said, Benbacer Laila, Zaid Abdelhamid   +11 more
doaj   +1 more source