Results 1 to 10 of about 826 (83)

Modular Synthesis and Biological Investigation of 5-Hydroxymethyl Dibenzyl Butyrolactones and Related Lignans

Molecules, 2018
Dibenzyl butyrolactone lignans are well known for their excellent biological properties, particularly for their notable anti-proliferative activities. Herein we report a novel, efficient, convergent synthesis of dibenzyl butyrolactone lignans utilizing ...
Lisa Ivy Pilkington, Nina Dempsey-Hibbert, Kathryn A Whitehead   +2 more
exaly   +3 more sources

Insights into additional lactone-based signaling circuits in Streptomyces: existence of acyl-homoserine lactones and LuxI/LuxR homologs in six Streptomyces species [PDF]

Frontiers in Microbiology
Acyl-homoserine lactones (AHLs), mediating pivotal physiological activities through quorum sensing (QS), have conventionally been considered limited to Gram-negative bacteria.
Amir Salehi-Najafabadi, Amir Salehi-Najafabadi, Sepand Tehrani Fateh, Sepand Tehrani Fateh, Ghasem Amoabediny, Ghasem Amoabediny, Javad Hamedi   +6 more
doaj   +2 more sources

Enantioselective Alkoxycarbonyl-Lactonization of Alkenes via the Merger of Photoredox and Copper Catalysis. [PDF]

Adv Sci (Weinh)
A highly enantioselective alkoxycarbonyl‐lactonization of alkenes is reported through a photoredox/copper dual‐catalyzed alkoxycarbonyl radical addition/cyclization reaction. Abstract The synthesis of ester derivatives represents one of the most significant and fundamental tasks in modern organic chemistry, and numerous methods have been developed in ...
Xiong Y, Zong Z, Xie W, Chen JQ, Zhou X, Wu J.   +5 more
europepmc   +2 more sources

Intramolecular PCET of α-Keto Acids: Synthesis of Trifluoromethyl Ketones via Ketyl Radicals. [PDF]

Chemistry
Decarboxylation of α‐keto acids have conventionally served as simple building blocks for the generation of nucleophilic acyl radicals. Herein, we demonstrate a distinct approach for this substrate class, showcasing the generation of ketyl radicals through a proton‐coupled electron transfer (PCET) mechanism.
Nabi RN, Jarquin KA, Karmakar A, Brunner KE, Kim DK.   +4 more
europepmc   +2 more sources

Chasing my Mavericks: Stereoselective Allylations, Cascade Reactions and Total Synthesis of Natural Products [PDF]

, 2022
Faltracco, Matteo
core  

Synthesis of Gamma-Butyrolactone Hormones Enables Understanding of Natural Product Induction. [PDF]

ACS Chem Biol, 2023
Wilbanks LE, Hennigan HE, Martinez-Brokaw CD, Lakkis H, Thormann S, Eggly AS, Buechel G, Parkinson EI.   +7 more
europepmc   +1 more source

A Concise and Divergent Approach to the Naturally Occurring Tetracyclic Clavine Alkaloids (+)-Lysergol, (+)-Lysergine, and (+)-Isolysergine. [PDF]

J Org Chem
Regni A, Bartoccini F, Piersanti G.
europepmc   +1 more source

Hydrogen Bond Promoted Carbonylative Lactonization of Alkenes. [PDF]

Chemistry
Qi X, Wang Y, Wu XF.
europepmc   +1 more source

Design and synthesis of butyrolactone V derivatives and its anti-inflammatory activity analysis. [PDF]

Chin Herb Med
Liu W, Zhang B, Hu Z, Yao S, Zhao Y, Wang F, Wang Y, Yang X, Yin J, Sun W, Tong Q, Gu L, Zhang Y.   +12 more
europepmc   +1 more source

Backbone ¹H, ¹³C and ¹⁵N assignments of the apo-acyl carrier protein (ACP₁) of Pseudomonas aeruginosa. [PDF]

Biomol NMR Assign, 2023
Rizzo M, Baggs E, Chowdhury AS, Nagarajan R, Warner LR.   +4 more
europepmc   +1 more source