Progress of the acyl-Coenzyme A thioester hydrolase family in cancer [PDF]
Frontiers in OncologyIn recent years, the acyl-Coenzyme A thioester hydrolase family (ACOTs) has received wide attention as a key link in lipid metabolism. This family is a class of enzymes that catalyze the hydrolysis of fatty acyl-Coenzyme A, disrupting the thioester bond ...
Lu Bai +4 more
doaj +2 more sources
Glycogen storage disease type Ia misdiagnosed as multiple acyl-coenzyme A dehydrogenase deficiency by mass spectrometry [PDF]
Frontiers in Pediatrics, 2022 ObjectiveTo report a case of glycogen storage disease (GSD) type Ia misdiagnosed as multiple acyl-coenzyme a dehydrogenase deficiency (MADD) by mass spectrometry.MethodsA 7 months old boy was admitted to our hospital for elevated transaminase levels ...
Juan Du +5 more
doaj +2 more sources
An update on the therapeutic implications of long-chain acyl-coenzyme A synthetases in nervous system diseases [PDF]
Frontiers in Neuroscience, 2022 Long-chain acyl-coenzyme A synthetases (ACSLs) are a family of CoA synthetases that activate fatty acid (FA) with chain lengths of 12–20 carbon atoms by forming the acyl-AMP derivative in an isozyme-specific manner.
Zhimin Wu +6 more
doaj +2 more sources
A novel mutation in ACADVL causing very long-chain acyl-coenzyme-A dehydrogenase deficiency in a South Asian pediatric patient: a case report and review of the literature [PDF]
Journal of Medical Case Reports, 2021 Background Very long-chain acyl-coenzyme-A dehydrogenase deficiency is a rare, severe life-threatening metabolic disorder of mitochondrial fatty acid oxidation, caused by mutations in ACADVL gene.
Visvalingam Arunath +5 more
doaj +2 more sources
Acyl-coenzyme A synthetases in metabolic control
Current Opinion in Lipidology, 2020 The 11 long-chain (ACSL) and very long chain acyl-coenzyme A (acyl-CoA) synthetases [(ACSVL)/fatty acid transport protein] are receiving considerable attention because it has become apparent that their individual functions are not redundant.
Jessica M. Ellis +3 more
openalex +4 more sources
A rapid assay of acyl-coenzyme A:lysolecithin acyltransferase activity
Journal of Lipid Research, 1980 A simple and rapid procedure for the assay of acyl-coenzyme A:1-acyl-sn-glycero-3-phosphocholine acyltransferase (lysolecithin acyltransferase, LLAT [EC 2.3.1.23]) activity in crude enzyme preparations is described.
K Hayase +3 more
doaj +3 more sources
Child Neurology: Medium-chain acyl-coenzyme A dehydrogenase deficiency [PDF]
Neurology, 2015 Medium-chain acyl-coenzyme A dehydrogenase (MCAD) deficiency (MCADD) is an autosomal recessive inherited fatty acid oxidation disorder. In MCADD, mitochondria cannot process medium-chain fatty acids via the β-oxidation pathway because of a lack of MCAD. While patients may be asymptomatic during the prenatal or immediate postnatal periods, patients will
Valerie Gartner +2 more
openalex +3 more sources
Anesthesia management in a patient with very long-chain acyl-Coenzyme A dehydrogenase deficiency [PDF]
JA Clinical Reports, 2020 Background In a patient with very long-chain acyl-Coenzyme A dehydrogenase (VLCAD) deficiency, metabolism of fatty acids is impaired and a supply of alternative energy is limited when glucose level is insufficient on starvation.
Haruyuki Yuasa +5 more
doaj +2 more sources
Correction: Pleiotropic Effect of AccD5 and AccE5 Depletion in Acyl-Coenzyme A Carboxylase Activity and in Lipid Biosynthesis in Mycobacteria. [PDF]
PLoS One, 2020 Lyonnet BB +6 more
europepmc +3 more sources
Anesthetic management of multiple acyl-coenzyme A dehydrogenase deficiency in a series of surgeries under general anesthesia: a case report. [PDF]
JA Clin Rep, 2021 Owaki-Nakano R +5 more
europepmc +3 more sources