Results 91 to 100 of about 57,830 (273)

Pantethine therapy dramatically rescues end‐stage failing heart in a patient with deficiency of coenzyme A biosynthesis

ESC Heart Failure, EarlyView.
Violette Goetz, Bruno Lefort, Magalie Barth, Naïg Gueguen, Céline Bris, Emmanuelle Blanchard, Isabelle Benz‐de Bretagne, Hélène Blasco, Marine Tardieu, François Labarthe   +9 more
wiley   +1 more source

Effects of HMG CoA reductase (HMGCR) deficiency on skeletal muscle development

The FEBS Journal, EarlyView.
Three skeletal muscle diseases are linked to HMGCR, a key enzyme in cholesterol synthesis. These diseases include a muscular dystrophy associated with pathogenic variants in the HMGCR gene, statin‐associated myopathy, and autoimmune anti‐HMGCR myopathy.
Mekala Gunasekaran, Hannah R. Littel, Natalya M. Wells, Johnnie Turner, Gloriana Campos, Sree Venigalla, Elicia A. Estrella, Partha S. Ghosh, Audrey L. Daugherty, Seth A. Stafki, Louis M. Kunkel, A. Reghan Foley, Sandra Donkervoort, Carsten G. Bönnemann, Laura Toledo‐Bravo de Laguna, Andres Nascimento, Daniel Natera‐de Benito, Isabelle Draper, Christine C. Bruels, Christina A. Pacak, Peter B. Kang   +20 more
wiley   +1 more source

The molecular mechanisms of defensive‐grade organic acid biosynthesis in ground beetles

Insect Molecular Biology, EarlyView.
Formic acid and methacrylic acid are the primary defensive chemicals in the pygidial gland secretions of Platynus angustatus and Pterostichus moestus, respectively. Comparative transcriptomics suggests the folate cycle and valine catabolism may be involved in the biosynthesis of formic acid and methacrylic acid, respectively.
Adam M. Rork, Sihang Xu, Athula Attygalle, Tanya Renner   +3 more
wiley   +1 more source

Control of fatty acid distribution in phosphatidylcholine of spinach leaves

Journal of Lipid Research, 1971
The acylation of lysophosphatidylcholine by enzyme preparations from spinach leaves was studied. The acylation reaction was followed by the incorporation of 14C-labeled fatty acids from the respective coenzyme A derivatives into phosphatidylcholine.
K.A. DEVOR, J.B. MUDD
doaj  

The road less taken: Dihydroflavonol 4‐reductase inactivation and delphinidin anthocyanin loss underpins a natural intraspecific flower colour variation

Molecular Ecology, EarlyView.
Abstract Visual cues are of critical importance for the attraction of animal pollinators, however, little is known about the molecular mechanisms underpinning intraspecific floral colour variation. Here, we combined comparative spectral analysis, targeted metabolite profiling, multi‐tissue transcriptomics, differential gene expression, sequence ...
Darren C. J. Wong, Zemin Wang, James Perkins, Xin Jin, Grace Emma Marsh, Emma Grace John, Rod Peakall   +6 more
wiley   +1 more source

Functional study of Phaeodactylum tricornutum Seipin highlights specificities of lipid droplets biogenesis in diatoms

New Phytologist, EarlyView.
Summary Diatoms are a major phylum of microalgae, playing crucial ecological roles. They derive from secondary endosymbiosis, leading to a complex intracellular architecture. Their ability to store oil in lipid droplets (LDs) upon unfavourable conditions has raised interest for applications, in particular biofuels, yet Lipid Droplet (LD) biogenesis ...
Damien Le Moigne, Marta Carletti, Chems Amari, Rachel Bonnarde, Fabien Richard, Catherine Albrieux, Mégane Mahieu, Matteo Arrighi, Grégory Si‐Larbi, Pierre‐Henri Jouneau, Valérie Gros, Mathilde Louwagie, Sylvaine Roy, Yangmin Gong, Yufang Pan, Hanhua Hu, Olivier Bastien, Juliette Jouhet, Alberto Amato, Eric Maréchal, Juliette Salvaing   +20 more
wiley   +1 more source

Acyl Coenzyme A Synthetase Long-Chain 1 (ACSL1) Gene Polymorphism (rs6552828) and Elite Endurance Athletic Status: A Replication Study

PLoS ONE, 2012
The aim of this study was to determine the association between the rs6552828 polymorphism in acyl coenzyme A synthetase (ACSL1) and elite endurance athletic status.
T. Yvert, Zi-hong He, C. Santiago, Yang Hu, Yan-chun Li, F. Gómez-Gallego, C. Fiuza-Luces, Z. Verde, Carlos A. Muniesa, J. Oliván, A. Santalla, J. Ruiz, A. Lucia   +12 more
semanticscholar   +1 more source

Transcriptomic analysis of the mandibular gland genes associated with reproductive dominance in Apis mellifera capensis Esch. parasitic workers

Physiological Entomology, EarlyView.
Biosynthesis of the fatty acid components of the Apis mellifera mandibular gland pheromones takes place in a stepwise manner. Differential gene expression in the mandibular gland tissue of workers from two subspecies of African honey bees with differing reproductive potentials and at two age groups was investigated.
Fiona Nelima Mumoki, Christian Walter Werner Pirk, Robin Michael Crewe, Abdullahi Ahmed Yusuf   +3 more
wiley   +1 more source

Molecular Phylogeny of Mouse‐Tailed Bats (Chiroptera: Rhinopomatidae): Evolutionary Insights Into a Desert‐Dwelling Family

Zoologica Scripta, EarlyView.
ABSTRACT The family Rhinopomatidae comprises six species of mouse‐tailed bats within the genus Rhinopoma, inhabiting arid regions of the Old World from western Africa to Myanmar. While their phylogenetic relationships have been explored through morphology and molecular analyses, many populations still remain insufficiently studied using molecular ...
Marek Uvizl, Peter Vallo, Petr Benda
wiley   +1 more source

Microbial diversity and function in the rhizosphere microbiome: Driving forces and monitoring approaches

Agrosystems, Geosciences &Environment, Volume 8, Issue 3, September 2025.
Abstract As an ecological unit, the rhizosphere microbiome preserves an enormous and largely unexplored diversity of microbes that play essential roles in plant health and soil functions. Omics technologies encompassing high‐throughput approaches such as metagenomics, metatranscriptomics, and metaproteomics provide helpful tools to unravel the ...
Chinenyenwa Fortune Chukwuneme, Olubukola Oluranti Babalola   +1 more
wiley   +1 more source