Results 101 to 110 of about 57,830 (273)
Journal of Lipid Research, 2006 Stearoyl-coenzyme A desaturase (SCD) is an endoplasmic reticulum (ER) protein that catalyzes the Δ9-cis desaturation of saturated fatty acids.
Weng Chi Man +3 more
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British Journal of Pharmacology, Volume 182, Issue 16, Page 3744-3766, August 2025.Background and Purpose Liver X receptors (LXRs) are promising therapeutic targets for alleviating Alzheimer's disease (AD) symptoms. We assessed the impact of the semi‐synthetic LXR agonist 22‐ketositosterol on disease progression in an AD mouse model.
Nikita Martens +15 more
wiley +1 more source
Ligand binding to the ACBD6 protein regulates the acyl-CoA transferase reactions in membranes
Journal of Lipid Research, 2015 The binding determinants of the human acyl-CoA binding domain-containing protein (ACBD) 6 and its function in lipid renewal of membranes were investigated. ACBD6 binds acyl-CoAs of a chain length of 6 to 20 carbons.
Eric Soupene, Frans A. Kuypers
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The Inhibition of the Fatty Acid Synthetase Multienzyme Complex of Yeast by Long‐Chain Acyl Coenzyme A Compounds [PDF]
, 1968 G. Lust, Frédéric Lynen
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ON THE MECHANISM OF DEHYDROGENATION OF FATTY ACYL DERIVATIVES OF COENZYME A
, 1956 F.L. Crane, Helmut Beinert
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, 2020 In the model plant Arabidopsis thaliana, a gene family of six members encodes acyl-Coenzyme A (CoA)-binding proteins (ACBPs). They are designated as ACBP1 to ACBP6 and they bind to acyl-CoA esters with different affinities. Two membrane-localized members, ACBP1 and ACBP2, share over 70% amino acid identity. Previous studies have shown they are involved
openaire +1 more source
Studies on medium-chain fatty acyl-coenzyme A synthetase. Enzyme fraction I: mechanism of reaction and allosteric properties [PDF]
, 1968 Jacob Bar‐Tana, G. Rose
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Cancer Medicine, Volume 14, Issue 13, July 2025.ABSTRACT Background Mitochondria have been linked with inflammatory colorectal cancer (CRC) development; however, the association between mitochondria‐related genes (MRGs) and CRC remains unknown. Aims To explore the causal relationship between MRGs and CRC, screen prognostic genes, conduct drug prediction analyses, and investigate the correlations ...
Limin Zhu +4 more
wiley +1 more source
Journal of Lipid Research, 2019 Diet, hormones, gene transcription, and posttranslational modifications control the hepatic metabolism of FAs; metabolic dysregulation causes chronic diseases, including cardiovascular disease, and warrants exploration into the mechanisms directing FA ...
Rosalind A. Coleman
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PDK4 and nutrient responses explain muscle specific manifestation in mitochondrial disease
Clinical and Translational Medicine, Volume 15, Issue 7, July 2025.Mitochondrial disease triggers opposite responses in different muscles. Mitochondrial integrated stress response (ISRmt) and aerobic glycolysis characterize large muscles. Eye muscles show no ISRmt but activate PDK4—inhibitor of glucose oxidation—thereby upregulating beta‐oxidation, which is non‐optimal in mitochondrial disease and can explain eye ...
Swagat Pradhan +6 more
wiley +1 more source