Results 111 to 120 of about 89,018 (342)

Production of a Brassica napus Low-Molecular Mass Acyl-Coenzyme A-Binding Protein in Arabidopsis Alters the Acyl-Coenzyme A Pool and Acyl Composition of Oil in Seeds1[C][W][OPEN]

Plant Physiology, 2014
An acyl-CoA-binding protein changes the acyl-CoA and oil composition in seeds of transgenic Arabidopsis. Low-molecular mass (10 kD) cytosolic acyl-coenzyme A-binding protein (ACBP) has a substantial influence over fatty acid (FA) composition in oilseeds,
O. Yurchenko, S. Singer, C. Nykiforuk, S. Gidda, R. Mullen, M. Moloney, R. Weselake   +6 more
semanticscholar   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Identification and characterization of an acyl-CoA:triterpene acyltransferase activity in rabbit and human tissues.

Journal of Lipid Research, 1991
Rabbit and human tissues contain substantial amounts of an unusual lipid, a fatty acid ester of a pentacyclic triterpene, that is a potent in vitro inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT). A possible origin of the triterpene ester is via
I Tabas, N Beatini, LL Chen, WC Su, MS Puar, S Dugar, JW Clader   +6 more
doaj   +1 more source

Time‐resolved multiparameter analytics on a cell‐free production platform for acyl‐CoA precursors

Analytical Science Advances, 2022
Cell‐free biosynthesis is emerging as a very attractive alternative for the production of market‐relevant molecules. The free combination of enzymes, regardless of where they are isolated from, raises the possibility to build more efficient synthetic ...
Dominic Maehler, Sandra Hoefgen, Ute Münchberg, Oliver J. Schmitz, Julia Rautschek, Ying Huang, Erik Freier, Vito Valiante   +7 more
doaj   +1 more source

Phloretin Suppresses Preadipocyte Differentiation by Targeting PPARγ/Transferrin to Activate Ferroptosis Signaling Pathway

Food Frontiers, EarlyView.
Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li, Qihui Zhu, Yang Li, Haiyu Zhao, Yi Bi, Chuanying Pan, Min Wang, Lin Han, Xianyong Lan   +8 more
wiley   +1 more source

ETFDH mutation involves excessive apoptosis and neurite outgrowth defect via Bcl2 pathway

Scientific Reports
The most common mutation in southern Chinese individuals with late-onset multiple acyl-coenzyme A dehydrogenase deficiency (MADD; a fatty acid metabolism disorder) is c.250G > A (p.Ala84Thr) in the electron transfer flavoprotein dehydrogenase gene (ETFDH)
Chuang-Yu Lin, Wen-Chen Liang, Yi-Chen Yu, Shin-Cheng Chang, Ming-Chi Lai, Yuh-Jyh Jong   +5 more
doaj   +1 more source

Functions of Coenzyme A and Acyl-CoA in Post-Translational Modification and Human Disease

Frontiers in Bioscience-Landmark
Coenzyme A (CoA) is synthesized from pantothenate, L-cysteine and adenosine triphosphate (ATP), and plays a vital role in diverse physiological processes. Protein acylation is a common post-translational modification (PTM) that modifies protein structure,
Jumin Xie, Zhang Yu, Ying Zhu, Mei Zheng, Yanfang Zhu   +4 more
doaj   +1 more source

Catalytic properties of MGAT3, a putative triacylgycerol synthases⃞

Journal of Lipid Research, 2007
Acyl-coenzyme A:monoacylglycerol acyltransferase 3 (MGAT3) is a member of the MGAT family of enzymes that catalyze the synthesis of diacylglycerol (DAG) from monoacylglycerol (MAG), a committed step in dietary fat absorption.
Jingsong Cao, Long Cheng, Yuguang Shi
doaj   +1 more source

RICE ACYL-COA-BINDING PROTEIN6 Affects Acyl-CoA Homeostasis and Growth in Rice

Rice, 2020
Backgrounds Acyl-coenzyme A (CoA) esters are important intermediates in lipid metabolism with regulatory properties. Acyl-CoA-binding proteins bind and transport acyl-CoAs to fulfill these functions.
Wei Meng, Lijian Xu, Zhi-Yan Du, Fang Wang, Rui Zhang, Xingshun Song, Sin Man Lam, Guanghou Shui, Yuhua Li, Mee-Len Chye   +9 more
doaj   +1 more source

Inhibitors of Pyruvate Carboxylase [PDF]

, 2010
This review aims to discuss the varied types of inhibitors of biotin-dependent carboxylases, with an emphasis on the inhibitors of pyruvate carboxylase.
Attwood, Paul V., Maurice, Martin St., Zeczycki, Tonya N.   +2 more
core   +2 more sources