A Human Model of Oligodendrocyte Development Shows MCL‐1 Influences Oligodendrocyte Morphogenesis
A unified model of oligodendrocyte differentiation from human embryonic stem cells revealed that MCL‐1 is critical for regulating the expression of oligodendrocyte‐related genes and the morphogenesis of myelinating oligodendrocytes. ABSTRACT Oligodendrocytes are the myelinating cells of the central nervous system.
Melanie Gil +2 more
wiley +1 more source
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
Contribution of the Distal Pocket Residue to the Acyl-Chain-Length Specificity of ( R )-Specific Enoyl-Coenzyme A Hydratases from Pseudomonas spp [PDF]
Takeharu Tsuge +6 more
openalex +1 more source
Multi-Method Quantification of Acetyl-Coenzyme A and Further Acyl-Coenzyme A Species in Normal and Ischemic Rat Liver. [PDF]
Tokarska-Schlattner M +14 more
europepmc +1 more source
Long-chain acyl-coenzyme A synthetase activity of spinach chloroplasts is concentrated in the envelope [PDF]
P. Grattan Roughan, C. R. Slack
openalex +1 more source
Oxidative Stress: Molecular Mechanisms, Diseases, and Therapeutic Targets
Oxidative stress occurs when the reactive oxygen species (ROS) production overwhelms the ROS scavenging, which lead to genomic instability, epigenetic regulation, proteostasis imbalance, and lipid peroxidation, subsequently causing the occurrence and development of numerous diseases. ABSTRACT Although the physiological level of reactive oxygen species (
Yi Qin +10 more
wiley +1 more source
Acyl-coenzyme A binding protein MoAcb1 regulates conidiation and pathogenicity in Magnaporthe oryzae. [PDF]
Cao N +6 more
europepmc +1 more source
Steady-state concentrations of coenzyme A, acetyl-coenzyme A and long-chain fatty acyl-coenzyme A in rat-liver mitochondria oxidizing palmitate [PDF]
PB Garland, David Shepherd, DW Yates
openalex +1 more source
The biosynthesis of galactolipids in red clover (Trifolium pratense) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry [PDF]
Galactolipids occur in all cells capable of the photosynthetic evolution of oxygen. The main galactolipids are monogalactosyl diglyceride (MGDG), digalactosyldiglyceride (DGDG) and sulfolipid (SL), MGDG being the most abundant.
Bycroft, Wesley
core
Sertraline‐Associated Riboflavin‐Responsive Lipid Storage Myopathy: Report of Two Case
Sertraline exposure can lead to an acquired riboflavin‐responsive multiple acyl‐CoA dehydrogenase deficiency (MADD). In patients with this acquired form of MADD, riboflavin supplementation can even lead to full clinical recovery and marked serological recovery before discontinuation of sertraline.
Aziz Shaibani, Alexis Taylor
wiley +1 more source

