Acyl-Coenzyme A: Cholesterol Acyltransferase Inhibition in Cancer Treatment [PDF]
Anticancer Research, 2019 Overexpression of acyl-coenzyme A:cholesterol acyltransferase (ACAT) results in increased cholesteryl ester levels and has been involved in a variety of cancer types.
Judyta Zabielska +2 more
semanticscholar +3 more sources
Acyl-coenzyme A:cholesterol acyltransferases. [PDF]
American Journal of Physiology-Endocrinology and Metabolism, 2009 The enzymes acyl-coenzyme A (CoA):cholesterol acyltransferases (ACATs) are membrane-bound proteins that utilize long-chain fatty acyl-CoA and cholesterol as substrates to form cholesteryl esters.
Ta-Yuan Chang +3 more
semanticscholar +4 more sources
A rapid assay of acyl-coenzyme A:lysolecithin acyltransferase activity
Journal of Lipid Research, 1980 A simple and rapid procedure for the assay of acyl-coenzyme A:1-acyl-sn-glycero-3-phosphocholine acyltransferase (lysolecithin acyltransferase, LLAT [EC 2.3.1.23]) activity in crude enzyme preparations is described.
K Hayase +3 more
doaj +4 more sources
Acyl‐coenzyme A organizes laterally in membranes and is recognized specifically by acyl‐coenzyme A binding protein [PDF]
FEBS Letters, 2003 Long chain acyl‐coenzyme A (acyl‐CoA) is a biochemically important amphiphilic molecule that is known to partition strongly into membranes by insertion of the acyl chain. At present, microscopically resolved evidence is lacking on how acyl‐CoA influences and organizes laterally in membranes. By atomic force microscopy (AFM) imaging of membranes exposed
Cohen Simonsen, A. +4 more
openaire +5 more sources
Key Roles in the Process of Extravasation and Colonization: Acyl-coenzyme A Synthetase Long-chain Family Member 4 and Polyunsaturated Lipids. [PDF]
MedComm (2020)MedComm, Volume 6, Issue 7, July 2025.
Han J, Zhang J, Chen Y.
europepmc +2 more sources
The pathophysiology of leg cramping during dialysis and the use of carnitine in its treatment
Physiological Reports, 2021 Leg cramping is a common side effect of hemodialysis, and this is frequently treated by the administration of carnitine, but this is not effective in every patient. Alkalosis is a key component of the etiology of leg cramping during hemodialysis sessions.
Akira Takahashi
doaj +1 more source
Acyl Coenzyme A Synthetase Regulation: Putative Role in Long‐Chain Acyl Coenzyme A Partitioning [PDF]
Obesity Research, 2004 AbstractObjective: Long‐chain acyl coenzyme A synthetase (ACSL) converts free fatty acids (FFAs) into their metabolizable long‐chain acyl coenzyme A (LC‐CoA) derivatives that are essential for FFA conversion to CO2, triglycerides, or complex lipids. ACSL‐1 is highly expressed in adipose tissue with broad substrate specificity.
Yan-Lin Wang +8 more
openaire +3 more sources
Evaluation of long-chain acyl-coenzyme A synthetase 4 (ACSL4) expression in human breast cancer
Research in Pharmaceutical Sciences, 2020 Background and purpose: Breast cancer (BC) is one of the major causes of female cancer-related death. It has recently been demonstrated that metabolic reprogramming including alteration in lipid metabolism is indicated in various types of cancer.
Negar Dinarvand +5 more
semanticscholar +1 more source
mBio, 2023 Members of the genus Mesorhizobium, which are core components of the rhizosphere and specific symbionts of legume plants, possess genes for acyl-homoserine lactone (AHL) quorum sensing (QS).
Zehui Suo +4 more
doaj +1 more source
Cell Death and Disease, 2020 Acyl coenzyme A binding protein (ACBP), also known as diazepam binding inhibitor (DBI) is a multifunctional protein with an intracellular action (as ACBP), as well as with an extracellular role (as DBI). The plasma levels of soluble ACBP/DBI are elevated
A. Joseph +34 more
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