Results 21 to 30 of about 89,018 (342)
Acyl Coenzyme A Synthetase Regulation: Putative Role in Long‐Chain Acyl Coenzyme A Partitioning [PDF]
AbstractObjective: Long‐chain acyl coenzyme A synthetase (ACSL) converts free fatty acids (FFAs) into their metabolizable long‐chain acyl coenzyme A (LC‐CoA) derivatives that are essential for FFA conversion to CO2, triglycerides, or complex lipids. ACSL‐1 is highly expressed in adipose tissue with broad substrate specificity.
Yan-Lin, Wang +8 more
openaire +2 more sources
The pathophysiology of leg cramping during dialysis and the use of carnitine in its treatment
Leg cramping is a common side effect of hemodialysis, and this is frequently treated by the administration of carnitine, but this is not effective in every patient. Alkalosis is a key component of the etiology of leg cramping during hemodialysis sessions.
Akira Takahashi
doaj +1 more source
Short-chain acyl-coenzyme A dehydrogenase deficiency [PDF]
Short-chain acyl-CoA dehydrogenase deficiency (SCADD) is a disorder of mitochondrial fatty acid oxidation that leads to the accumulation of butyrylcarnitine and ethylmalonic acid in blood and urine. Originally described with a relatively severe phenotype, most patients are now diagnosed through newborn screening by tandem mass spectrometry and remain ...
Reena, Jethva +2 more
openaire +2 more sources
Acyl coenzyme A binding protein (ACBP), also known as diazepam binding inhibitor (DBI) is a multifunctional protein with an intracellular action (as ACBP), as well as with an extracellular role (as DBI). The plasma levels of soluble ACBP/DBI are elevated
A. Joseph +34 more
semanticscholar +1 more source
Members of the genus Mesorhizobium, which are core components of the rhizosphere and specific symbionts of legume plants, possess genes for acyl-homoserine lactone (AHL) quorum sensing (QS).
Zehui Suo +4 more
doaj +1 more source
Acyl‐coenzyme A organizes laterally in membranes and is recognized specifically by acyl‐coenzyme A binding protein [PDF]
Long chain acyl‐coenzyme A (acyl‐CoA) is a biochemically important amphiphilic molecule that is known to partition strongly into membranes by insertion of the acyl chain. At present, microscopically resolved evidence is lacking on how acyl‐CoA influences and organizes laterally in membranes. By atomic force microscopy (AFM) imaging of membranes exposed
Cohen Simonsen, A. +4 more
openaire +4 more sources
Acyl-CoA carboxylases play key roles in primary and secondary metabolism. However, the regulation of ACCase genes transcription in Streptomyces spp. remains unclear.
Mengya Lyu +6 more
semanticscholar +1 more source
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog +12 more
wiley +1 more source
The Structural Basis of Coenzyme A Recycling in a Bacterial Organelle. [PDF]
Bacterial Microcompartments (BMCs) are proteinaceous organelles that encapsulate critical segments of autotrophic and heterotrophic metabolic pathways; they are functionally diverse and are found across 23 different phyla. The majority of catabolic BMCs (
Erbilgin, Onur +2 more
core +3 more sources
Lipid droplets (LDs) function as intracellular storage depots of neutral lipids. Recently, we identified long-chain acyl-coenzyme A synthetase 3 (ACSL3) as a major LD-associated protein in the human hepatocyte cell line HuH7.
Yasuyuki Fujimoto +10 more
doaj +1 more source

