Results 311 to 320 of about 89,018 (342)

Acyl-Coenzyme A Binding Protein Expression Alters Liver Fatty Acyl-Coenzyme A Metabolism

Biochemistry, 2005
Although studies in vitro and in yeast suggest that acyl-CoA binding protein ACBP may modulate long-chain fatty acyl-CoA (LCFA-CoA) distribution, its physiological function in mammals is unresolved. To address this issue, the effect of ACBP on liver LCFA-CoA pool size, acyl chain composition, distribution, and transacylation into more complex lipids ...
Huan, Huang, Barbara P, Atshaves, Andrey, Frolov, Ann B, Kier, Friedhelm, Schroeder   +4 more
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Acyl coenzyme A dependent retinol esterification by acyl coenzyme A:diacylglycerol acyltransferase 1

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2005
We provide biochemical evidence that enzymes involved in the synthesis of triacylglycerol, namely acyl coenzyme A:diacylglycerol acyltransferase (DGAT) and acyl coenzyme A:monoacylglycerol acyltransferase (MGAT), are capable of carrying out the acyl coenzyme A:retinol acyltransferase (ARAT) reaction.
Michael D, Orland, Kamran, Anwar, Debra, Cromley, Ching-Hsuen, Chu, Luping, Chen, Jeffrey T, Billheimer, M Mahmood, Hussain, Dong, Cheng   +7 more
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Inhibitors of Acyl-Coenzyme A: Cholesterol Acyltransferase

Current Drug Target -Cardiovascular & Hematological Disorders, 2005
Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that catalyzes the formation of cholesterol esters from cholesterol and fatty acyl-coenzyme A. Animal experiments showed that ACAT inhibitors reduce plasma cholesterol levels by suppressing absorption of dietary cholesterol and by suppressing the assembly and secretion of ...
Akira, Miyazaki, Tomoko, Kanome, Takuya, Watanabe   +2 more
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ETFDH Mutations and Flavin Adenine Dinucleotide Homeostasis Disturbance Are Essential for Developing Riboflavin‐Responsive Multiple Acyl–Coenzyme A Dehydrogenation Deficiency

Annals of Neurology, 2018
Riboflavin‐responsive multiple acyl–coenzyme A dehydrogenation deficiency (RR‐MADD) is an inherited fatty acid metabolism disorder mainly caused by genetic defects in electron transfer flavoprotein–ubiquinone oxidoreductase (ETF:QO).
Jingwen Xu, Duoling Li, J. Lv, Xuebi Xu, B. Wen, P. Lin, Fuchen Liu, K. Ji, Jingli Shan, Hong-hao Li, Wei Li, Yuying Zhao, Dandan Zhao, J. Pok, Chuanzhu Yan   +14 more
semanticscholar   +1 more source

Characterization of Lipid Binding Properties of Plasmodium falciparum Acyl-Coenzyme A Binding Proteins and Their Competitive Inhibition by Mefloquine.

ACS Chemical Biology, 2019
Malaria remains a worldwide concern in terms of morbidity and mortality. Limited understanding of the Plasmodium proteome makes it challenging to control malaria. Understanding of the expression and functions of different Plasmodium proteins will help in
Abhishek Kumar, D. Ghosh, Jamshaid Ali, A. Ranjan   +3 more
semanticscholar   +1 more source

Acyl-coenzyme A: cholesterol acyltransferase family

Frontiers of Biology in China, 2008
The enzymes of the acyl-coenzyme A: cholesterol acyltransferase (ACAT) family are responsible for the in vivo synthesis of neutral lipids. They are potential drug targets for the intervention of atherosclerosis, hyperlipidemia, obesity, type II diabetes and even Alzheimer’s disease.
Yali Liu, Zhanyun Guo
openaire   +1 more source

Fatty Acyl-Coenzyme A Dehydrogenases

Biochemical Society Transactions, 1978
The general enzymology of @-oxidation has suffered extraordinary neglect since the broad outlines of the pathway were established in the 1950’s. For the acyl-CoA dehydrogenases the contributions from the Institute for Enzyme Research at the University of Wisconsin still represent the major part of our knowledge.
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Sensor for free fatty acids based on acyl coenzyme-a synthetase and acyl coenzyme-a oxidase

Analytica Chimica Acta, 1989
Abstract The measurement is based on monitoring dissolved oxgyen consumed by the two sequential reactions catalyzed by the enzymes immobilized in photo-cross-linkable poly (vinyl alcohol) resin (PVA-SbQ). A linear correlation was observed between current decrease and 0.3–2.6 mM oleic or palmitic acid.
Koji Sode, Eiichi Tamiya, Isao Karube, Yuko Kameda   +3 more
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Multiple acyl-coenzyme A carboxylases in Pseudomonas citronellolis

Biochemistry, 1976
Pseudomonas citronellolis was shown to contain four different acyl-coenzyme A carboxylases, including acetyl-, propionyl-, 3-methylcrotonyl-, and geranyl-CoA carboxylases, when grown on the appropriate carbon sources. Acetyl-CoA carboxylase activity in crude extracts was stimulated approximately 40-fold by inclusion of 0.4-0.5 M ammonium sulfate in the
M L, Hector, R R, Fall
openaire   +2 more sources

Hyperuricemia in medium-chain acyl-coenzyme A dehydrogenase deficiency

The Journal of Pediatrics, 1992
Six infants and children with medium-chain acyl-coenzyme A dehydrogenase deficiency were found to have hyperuricemia during an acute episode. Hyperuricemia may be a clue to the diagnosis of medium-chain acyl-coenzyme A dehydrogenase deficiency.
A, Davidson-Mundt, A S, Luder, C L, Greene   +2 more
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