Results 41 to 50 of about 57,830 (273)
Plants, 2020 The spectral quality and intensity of light, photoperiodism, and other environmental factors have profound impacts on the metabolic composition of light-dependent higher plants.
Muthusamy Muthusamy +10 more
doaj +1 more source
Engineered Production of Short-Chain Acyl-Coenzyme A Esters in Saccharomyces cerevisiae.
ACS Synthetic Biology, 2018 Short-chain acyl-coenzyme A esters serve as intermediate compounds in fatty acid biosynthesis, and the production of polyketides, biopolymers and other value-added chemicals. S.
Nicolas Krink-Koutsoubelis +12 more
semanticscholar +1 more source
Immunolocalization of Acyl-Coenzyme A:CholesterolO-Acyltransferase in Macrophages [PDF]
Journal of Biological Chemistry, 1998 Macrophages in atherosclerotic lesions accumulate large amounts of cholesteryl-fatty acyl esters ("foam cell" formation) through the intracellular esterification of cholesterol by acyl-coenzyme A:cholesterol O-acyltransferase (ACAT). In this study, we sought to determine the subcellular localization of ACAT in macrophages.
Ira Tabas +8 more
openaire +3 more sources
eLife, 2013 Large Ca transients cause massive endocytosis (MEND) in BHK fibroblasts by nonclassical mechanisms. We present evidence that MEND depends on mitochondrial permeability transition pore (PTP) openings, followed by coenzyme A (CoA) release, acyl CoA ...
Donald W Hilgemann +4 more
doaj +1 more source
Roles of acyl‐coenzyme A synthetase family members in airway epithelia cells
Clinical and Translational Discovery, 2023 Background The fundamental initial step in the metabolic process of fatty acids (FA) is facilitated by Acyl‐coenzyme A synthetase (ACS). ACS enables FAs to engage in both anabolic and catabolic pathways by creating thioester bonds with CoA, thus ...
Linlin Zhang +7 more
doaj +1 more source
Metabolic and tissue-specific regulation of acyl-CoA metabolism. [PDF]
PLoS ONE, 2015 Acyl-CoA formation initiates cellular fatty acid metabolism. Acyl-CoAs are generated by the ligation of a fatty acid to Coenzyme A mediated by a large family of acyl-CoA synthetases (ACS).
Jessica M Ellis +2 more
doaj +1 more source
Organic Letters, 2015 A chemoenzymatic approach to generate fully functional acyl coenzyme A molecules that are then used as substrates to drive in situ acyl transfer reactions is described.
V. Agarwal +6 more
semanticscholar +1 more source
Advanced Science, EarlyView.The research reveals that polysulfide anions (K2Sx), which serve as reducing catalysts, can also effectively act as sulfur reagents, providing the formation of C(sp3)─S bonds through photoredox catalysis with an oxidative photocatalyst tetrabutylammonium decatungstate (TBADT) and dual hydrogen atom transfer (DHAT) process.
Chao Zhou +8 more
wiley +1 more source
Short-Chain Acyl-Coenzyme A Dehydrogenase Deficiency in Mice [PDF]
Pediatric Research, 1989 A murine model for short-chain acyl-coenzyme A dehydrogenase (SCAD) deficiency has been identified and characterized in BALB/cByJ mice. These mice have undetectable SCAD activity, severe organic aciduria; excreting ethylmalonic and methylsuccinic acids and N-butyrylglycine, and develop a fatty liver upon fasting or dietary fat challenge.
Philip A. Wood +5 more
openaire +2 more sources
Advanced Science, EarlyView.γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang +10 more
wiley +1 more source