Results 61 to 70 of about 89,018 (342)
Our goal was to assess the validity of the enrichments of plasma free palmitate and intramuscular (IM) fatty acid metabolites as precursors for calculating the IM triglyceride fractional synthetic rate.
Xiao-jun Zhang +7 more
doaj +1 more source
Biosynthesis of α-Tocopherol and Plastoquinone-9 in spinach chloroplasts [PDF]
Prenylation and methylation reaction in al biosynthesis is localized in the envelope membranes of the chloroplasts, while PQ-9 biosynthesis takes place in the envelope membranes and also in the thylakoid membranes.
Mazliak, P. +2 more
core +1 more source
A Single LC-MS/MS Analysis to Quantify CoA Biosynthetic Intermediates and Short-Chain Acyl CoAs
Coenzyme A (CoA) is an essential cofactor for dozens of reactions in intermediary metabolism. Dysregulation of CoA synthesis or acyl CoA metabolism can result in metabolic or neurodegenerative disease.
Anthony E. Jones +5 more
doaj +1 more source
Activation of hypolipidaemic drugs to acyl-coenzyme A thioesters [PDF]
Compounds possessing the characteristics of CoA thioesters of the hypolipidaemic peroxisome proliferators clofibric acid, nafenopin and ciprofibrate were formed on incubation of the drugs with rat liver microsomal fractions, ATP and CoA. The reactivity of the drugs correlated with their pharmacological potency. It is proposed that the active species of
BRONFMAN, M, AMIGO, L, MORALES, MN
openaire +2 more sources
Remnants of an ancient metabolism without phosphate [PDF]
Phosphate is essential for all living systems, serving as a building block of genetic and metabolic machinery. However, it is unclear how phosphate could have assumed these central roles on primordial Earth, given its poor geochemical accessibility.
Goldford, Joshua E. +3 more
core +1 more source
Control of fatty acid distribution in phosphatidylcholine of spinach leaves
The acylation of lysophosphatidylcholine by enzyme preparations from spinach leaves was studied. The acylation reaction was followed by the incorporation of 14C-labeled fatty acids from the respective coenzyme A derivatives into phosphatidylcholine.
K.A. DEVOR, J.B. MUDD
doaj +1 more source
The spectral quality and intensity of light, photoperiodism, and other environmental factors have profound impacts on the metabolic composition of light-dependent higher plants.
Muthusamy Muthusamy +10 more
doaj +1 more source
Structure and substrate selectivity of the 750-kDa α6β6 holoenzyme of geranyl-CoA carboxylase. [PDF]
Geranyl-CoA carboxylase (GCC) is essential for the growth of Pseudomonas organisms with geranic acid as the sole carbon source. GCC has the same domain organization and shares strong sequence conservation with the related biotin-dependent carboxylases 3 ...
Huang, Christine S +4 more
core +2 more sources
Dysregulated lipid metabolism contributes to cancer progression. Our previous study indicates that long-chain fatty acyl-Co A synthetase (ACSL) 3 is essential for lipid upregulation induced by endoplasmic reticulum stress.
Wei-Ching Chen +5 more
semanticscholar +1 more source
Short-Chain Acyl-Coenzyme A Dehydrogenase Deficiency in Mice [PDF]
A murine model for short-chain acyl-coenzyme A dehydrogenase (SCAD) deficiency has been identified and characterized in BALB/cByJ mice. These mice have undetectable SCAD activity, severe organic aciduria; excreting ethylmalonic and methylsuccinic acids and N-butyrylglycine, and develop a fatty liver upon fasting or dietary fat challenge.
P A, Wood +5 more
openaire +2 more sources

