Results 71 to 80 of about 57,830 (273)

Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family

Journal of Lipid Research, 2004
By consensus, the acyl-CoA synthetase (ACS) community, with the advice of the human and mouse genome nomenclature committees, has revised the nomenclature for the mammalian long-chain acyl-CoA synthetases.
Douglas G. Mashek, Karin E. Bornfeldt, Rosalind A. Coleman, Johannes Berger, David A. Bernlohr, Paul Black, Concetta C. DiRusso, Steven A. Farber, Wen Guo, Naohiro Hashimoto, Varsha Khodiyar, Frans A. Kuypers, Lois J. Maltais, Daniel W. Nebert, Alessandra Renieri, Jean E. Schaffer, Andreas Stahl, Paul A. Watkins, Vasilis Vasiliou, Tokuo T. Yamamoto   +19 more
doaj  

Metabolism of propionic acid to a novel acyl-coenzyme A thioester by mammalian cell lines and platelets[S]

Journal of Lipid Research, 2015
Metabolism of propionate involves the activated acyl-thioester propionyl-CoA intermediate. We employed LC-MS/MS, LC-selected reaction monitoring/MS, and LC-high-resolution MS to investigate metabolism of propionate to acyl-CoA intermediates.
N. Snyder, Sankha S. Basu, A. Worth, C. Mesaros, I. Blair   +4 more
semanticscholar   +1 more source

Inhibition of Steryl Glycoside Biosynthesis by Acyl Coenzyme A and by Digitonin [PDF]

Plant Physiology, 1980
ATP, GTP, CoA, Mg(2+), and Mn(2+) did not inhibit biosynthesis of steryl glycoside and acylated steryl glycoside when added singly to enzyme preparations from spinach leaves. The combination of ATP (but not GTP), CoA, and Mg(2+) or Mn(2+) caused marked inhibition, especially of steryl glycoside biosynthesis, when reaction mixture concentrations of the ...
Raymond E. Garcia, J. Brian Mudd
openaire   +3 more sources

Computational modelling of myocardial metabolism in patients with advanced heart failure

European Journal of Heart Failure, EarlyView.
LV, left ventricular; LVAD, left ventricular assist device; LVEF, left ventricular ejection fraction. Abstract Aims Perturbations of myocardial metabolism and energy depletion are well‐established hallmarks of heart failure (HF), yet methods for their systematic assessment remain limited in humans.
Niklas Beyhoff, Vera M. Braun, Marieluise Kirchner, Lucy E.M. Finnigan, Christoph Knosalla, István Baczkó, Evgenij Potapov, Ulrich Kintscher, Tilman Grune, Titus Kuehne, Hermann‐Georg Holzhütter, Philipp Mertins, Damian J. Tyler, Hendrik Milting, Betty Raman, Oliver J. Rider, Stefan Neubauer, Nikolaus Berndt   +17 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Functions of Coenzyme A and Acyl-CoA in Post-Translational Modification and Human Disease

Frontiers in Bioscience-Landmark
Coenzyme A (CoA) is synthesized from pantothenate, L-cysteine and adenosine triphosphate (ATP), and plays a vital role in diverse physiological processes. Protein acylation is a common post-translational modification (PTM) that modifies protein structure,
Jumin Xie, Zhang Yu, Ying Zhu, Mei Zheng, Yanfang Zhu   +4 more
doaj   +1 more source

ACYL-COENZYME A FORMATION OF SIMVASTATIN IN MOUSE LIVER PREPARATIONS [PDF]

Drug Metabolism and Disposition, 2006
Formation of an acyl-CoA thioester has been proposed, but not directly demonstrated, to be a key step in mediating both lactonization and atypical beta-oxidation of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors. Here, we describe studies to characterize formation of acyl-CoA thioesters in vitro in mouse liver preparations using the hydroxy acid ...
Raju Subramanian, Sean Yu, Thomayant Prueksaritanont, Chunze Li   +3 more
openaire   +3 more sources

ETFDH mutation involves excessive apoptosis and neurite outgrowth defect via Bcl2 pathway

Scientific Reports
The most common mutation in southern Chinese individuals with late-onset multiple acyl-coenzyme A dehydrogenase deficiency (MADD; a fatty acid metabolism disorder) is c.250G > A (p.Ala84Thr) in the electron transfer flavoprotein dehydrogenase gene (ETFDH)
Chuang-Yu Lin, Wen-Chen Liang, Yi-Chen Yu, Shin-Cheng Chang, Ming-Chi Lai, Yuh-Jyh Jong   +5 more
doaj   +1 more source

RICE ACYL-COA-BINDING PROTEIN6 Affects Acyl-CoA Homeostasis and Growth in Rice

Rice, 2020
Backgrounds Acyl-coenzyme A (CoA) esters are important intermediates in lipid metabolism with regulatory properties. Acyl-CoA-binding proteins bind and transport acyl-CoAs to fulfill these functions.
Wei Meng, Lijian Xu, Zhi-Yan Du, Fang Wang, Rui Zhang, Xingshun Song, Sin Man Lam, Guanghou Shui, Yuhua Li, Mee-Len Chye   +9 more
doaj   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source