Results 71 to 80 of about 46,261 (289)
Only Acyl Carrier Protein 1 (AcpP1) Functions in Pseudomonas aeruginosa Fatty Acid Synthesis
Frontiers in Microbiology, 2017 The genome of Pseudomonas aeruginosa contains three open reading frames, PA2966, PA1869, and PA3334, which encode putative acyl carrier proteins, AcpP1, AcpP2, and AcpP3, respectively.
Jin-Cheng Ma +4 more
doaj +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Thematic Review Series: Glycerolipids. Acyltransferases in bacterial glycerophospholipid synthesis*
Journal of Lipid Research, 2008 Phospholipid biosynthesis is a vital facet of bacterial physiology that begins with the synthesis of the fatty acids by a soluble type II fatty acid synthase.
Yong-Mei Zhang, Charles O. Rock
doaj +1 more source
Structure, function and dynamics in acyl carrier proteins
PLOS ONE, 2019 Carrier proteins are four-helix bundles that covalently hold metabolites and secondary metabolites, such as fatty acids, polyketides and non-ribosomal peptides. These proteins mediate the production of many pharmaceutically important compounds including antibiotics and anticancer agents.
Rohit Farmer +2 more
openaire +4 more sources
Advanced Synthesis &Catalysis, EarlyView.Although this article formally presents a regioselective photochemical ring enlargement of thietanes into 1,2‐ or 1,3‐dithianes, time‐dependent density functional theory calculations have revealed that 1,3‐dithianes are in fact formed thought photoinduced hydrogen atom transfers from 1,2‐dithianes initially resulting from the ring enlargement using ...
Gabriel Cormier +5 more
wiley +1 more source
Advanced Science, EarlyView.These findings suggest that UCP2 promotes LD formation and release in acinar cells by upregulating ACSL3 expression. This alteration in the local lipid metabolic environment indirectly drives the MMT process. Additionally, UCP2 may regulate the acetylation of Smad3 through Sirt1, enhancing its nuclear activity and activating the TGF‐β/ Smad3 signaling ...
Kunpeng Wang +9 more
wiley +1 more source
eLife, 2016 Mitochondrial fatty acid synthesis (FASII) and iron sulfur cluster (FeS) biogenesis are both vital biosynthetic processes within mitochondria. In this study, we demonstrate that the mitochondrial acyl carrier protein (ACP), which has a well-known role in
Jonathan G Van Vranken +6 more
doaj +1 more source
Advanced Science, EarlyView.Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
Journal of Lipid Research, 1984 The membrane localization and properties of the Rhodopseudomonas sphaeroides sn-glycerol-3-phosphate acyltransferase have been examined utilizing enzymatically prepared acyl-acyl carrier protein (acyl-ACP) substrates as acyl donors for sn-glycerol-3 ...
CL Cooper, DR Lueking
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Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia
Advanced Science, EarlyView.Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji +12 more
wiley +1 more source