Results 81 to 90 of about 80,359 (315)

Acyl Carrier Protein 3 Is Involved in Oxidative Stress Response in Pseudomonas aeruginosa

open access: yesFrontiers in Microbiology, 2018
The human opportunistic pathogen Pseudomonas aeruginosa expresses three acyl carrier proteins (ACPs): AcpP, Acp1, and Acp3. The function of AcpP in membrane fatty acid synthesis (FAS) was confirmed recently, but the physiological roles of Acp1 and Acp3 ...
Wei Chen   +5 more
doaj   +1 more source

Ralstonia solanacearum RSp0194 Encodes a Novel 3-Keto-Acyl Carrier Protein Synthase III. [PDF]

open access: yesPLoS ONE, 2015
Fatty acid synthesis (FAS), a primary metabolic pathway, is essential for survival of bacteria. Ralstonia solanacearum, a β-proteobacteria member, causes a bacterial wilt affecting more than 200 plant species, including many economically important plants.
Ya-Hui Mao   +4 more
doaj   +1 more source

Growth of Enterococcus faecalis ∆plsX strains is restored by increased saturated fatty acid synthesis

open access: yesmSphere, 2023
The Enterococcus faecalis acyl-acyl carrier protein (ACP) phosphate acyltransferase PlsX plays an important role in phospholipid synthesis and exogenous fatty acid incorporation.
Qi Zou, Huijuan Dong, John E. Cronan
doaj   +1 more source

Biocatalytic Synthesis of Stereospecific Triketide Lactones using Polyketide Synthases [PDF]

open access: yes, 2016
Polyketide synthases are modular enzymes that create and modify large acyl chains. The domains and modules of polyketide synthases allow us to create molecules that resemble naturally occurring products by applying a biocatalytic in vitro in vivo ...
Alexander, Bradley
core   +1 more source

Azabicyclo[1.1.0]butyl‐Substituted Sulfonimidoyl Fluoride: Electrophilic Hub Bridging Late‐Stage Azetidine Incorporation with Sufex Chemistry

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
GA: Strained small motifs and SuFEx hubs are of increasing importance in drug discovery to enable efficient late‐stage functionalization. Here, the synthesis of bench‐stable azabicyclo[1.1.0]butyl‐substituted sulfonimidoyl fluoride as an electrophilic hub with dual activation mode is reported.
Defne Serbetci   +5 more
wiley   +1 more source

Effects of detergents on activity, thermostability and aggregation of immobilized lipases [PDF]

open access: yes, 2014
Predmetom tejto diplomovej práce bolo štúdium vplyvu detergentov na aktivitu, termostabilitu a agregáciu voľnej a imobilizovanej formy komerčného preparátu lipázy izolovanej z mikroskopickej huby Rhizopus arrhizus. Teoretická časť obsahuje ucelenú rešerš
Bančáková, Anna
core  

The pleiotropic transcriptional regulator NlpR contributes to the modulation of nitrogen metabolism, lipogenesis and triacylglycerol accumulation in oleaginous rhodococci [PDF]

open access: yes, 2017
The regulatory mechanisms involved in lipogenesis and triacylglycerol (TAG) accumulation are largely unknown in oleaginous rhodococci. In this study a regulatory protein (here called NlpR: Nitrogen lipid Regulator), which contributes to the modulation of
Alvarez, Hector Manuel   +4 more
core   +1 more source

Synthesis of 3,4‐Dihydroquinazolinones via Base‐Promoted Formal [4 + 2] Cycloadditions

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
In this work a straightforward, metal‐free and general protocol for the synthesis of 3,4‐dihydroquinazolin‐2(1H)‐ones is described. From 2‐chloromethyl anilines upon treatment with a base an aza‐o‐quinone methide is in situ generated. This highly reactive intermediate readily reacts through [4 + 2] cycloaddition with isocyanates affording 32 ...
Sergio Torres‐Oya   +2 more
wiley   +1 more source

Integrating Visible‐Light Photocatalysis and Enzymes for the Stereoselective Synthesis of Alcohols and Amines

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
The integration between visible‐light photocatalysis and biocatalysis has the potential to greatly improve modern organic synthesis by combining the production of valuable synthetic intermediates under mild photochemical conditions with the high degree of stereoselectivity reached by enzymes. The review collects the recent efforts in the photoenzymatic
Stefano Parisotto, Cristina Prandi
wiley   +1 more source

ACBP and cholesterol differentially alter fatty acyl CoA utilization by microsomal ACAT

open access: yesJournal of Lipid Research, 2003
Microsomal acyl CoA:cholesterol acyltransferase (AC57) is stimulated in vitro and/or in intact cells by proteins that bind and transfer both substrates, cholesterol, and fatty acyl CoA.
Hsu Chao   +4 more
doaj  

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