Results 91 to 100 of about 31,319 (243)

The Crystal Structure of Human Transport and Golgi Organization 2 Homolog (TANGO2) Protein Reveals an αββα‐Fold Arrangement

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Transport and Golgi Organization 2 Homolog (TANGO2) protein deficiency disorder (TDD) is a rare autosomal recessive disorder characterized by multi‐systemic abnormalities and significant phenotypic variability including neurodevelopmental delay, seizures, intermittent ataxia, hypothyroidism, rhabdomyolysis, life‐threatening metabolic ...
Anne Cooper, Alyssa Powers, Kevin P. Battaile, Al‐Walid Mohsen, David K. Johnson, Scott Lovell, Lina Ghaloul‐Gonzalez   +6 more
wiley   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells*s⃞

Journal of Lipid Research, 2008
Human acyl-coenzyme A binding domain-containing member 6 (ACBD6) is a modular protein that carries an acyl-CoA binding domain at its N terminus and two ankyrin motifs at its C terminus.
Eric Soupene, Vladimir Serikov, Frans A. Kuypers   +2 more
doaj   +1 more source

Differential gene expression in Chorthippus parallelus (Zetterstedt, 1821) (Orthoptera: Acrididae: Gomphocerinae) induced by Wolbachia infection

Insect Science, EarlyView.
Distinct lineages of the grasshopper Chorthippus parallelus (Orthoptera: Acrididae) form a well‐known hybrid zone (HZ) in the Pyrenees mountain range; the Iberian endemism C. p. erythropus (Cpe) and the subspecies C. p. parallelus, (Cpp) widely distributed throughout the rest of Europe. Both subspecies differ in diverse traits, including the strains of
Patricia Jiménez‐Florido, Mónica Aquilino, David Buckley, José L. Bella, Rosario Planelló   +4 more
wiley   +1 more source

Effect of pregnancy and lactation on lipoprotein and cholesterol metabolism in the rat

Journal of Lipid Research, 1998
Origins of hyperlipidemia and cholestasis that occur during pregnancy were investigated by examining expression of key elements related to plasma and hepatic cholesterol metabolism during pregnancy, lactation, and post-lactation in the rat model.
Jeffery L. Smith, Steven R. Lear, Trudy M. Forte, William Ko, Mara Massimi, Sandra K. Erickson   +5 more
doaj   +1 more source

Gut Microbiota Regulate Lipid Metabolism via the Bile Acid Pathway: Resistance to Hypoxia in Gansu Zokor (Eospalax cansus)

Integrative Zoology, EarlyView.
The gut microbiota regulates lipid metabolism of Gansu zokor (Eospalax cansus) through the bile acid pathway in hypoxic environments, reflecting the unique survival strategy of subterranean rodents to maintain lipid metabolism homeostasis and flexible energy metabolism in hypoxic environments.
Maohong Yang, Yingying Zhang, Zhuohang Li, Tianyi Liu, Jianping He, Jingang Li   +5 more
wiley   +1 more source

The Inhibition of the Fatty Acid Synthetase Multienzyme Complex of Yeast by Long‐Chain Acyl Coenzyme A Compounds [PDF]

, 1968
G. Lust, Frédéric Lynen
openalex   +1 more source

Comparative Analysis of Heat Exposure‐Induced Molecular Changes in Two Turtle Species with Contrasting Thermal Adaptations

Integrative Zoology, EarlyView.
Protein processing in the endoplasmic reticulum is highlighted in response to heat stress in Platysternon megacephalum. Under heat stress, the up‐regulation of genes such as CHOP in protein processing in the endoplasmic reticulum pathway, along with the suppression of energy and lipid metabolism and the up‐regulation of JARID2 expression, leads to ...
Jian Hong, Yangchun Gao, Jiaxuan Li, Yan Ge, Yufeng Wei, Youqiang Yin, Qianru Liang, Shiping Gong   +7 more
wiley   +1 more source

Effects of HMG CoA reductase (HMGCR) deficiency on skeletal muscle development

The FEBS Journal, EarlyView.
Three skeletal muscle diseases are linked to HMGCR, a key enzyme in cholesterol synthesis. These diseases include a muscular dystrophy associated with pathogenic variants in the HMGCR gene, statin‐associated myopathy, and autoimmune anti‐HMGCR myopathy.
Mekala Gunasekaran, Hannah R. Littel, Natalya M. Wells, Johnnie Turner, Gloriana Campos, Sree Venigalla, Elicia A. Estrella, Partha S. Ghosh, Audrey L. Daugherty, Seth A. Stafki, Louis M. Kunkel, A. Reghan Foley, Sandra Donkervoort, Carsten G. Bönnemann, Laura Toledo‐Bravo de Laguna, Andres Nascimento, Daniel Natera‐de Benito, Isabelle Draper, Christine C. Bruels, Christina A. Pacak, Peter B. Kang   +20 more
wiley   +1 more source

Studies on medium-chain fatty acyl-coenzyme A synthetase. Enzyme fraction I: mechanism of reaction and allosteric properties [PDF]

, 1968
Jacob Bar‐Tana, G. Rose
openalex   +1 more source