Results 101 to 110 of about 2,608,587 (304)
RICE ACYL-COA-BINDING PROTEIN6 Affects Acyl-CoA Homeostasis and Growth in Rice
Backgrounds Acyl-coenzyme A (CoA) esters are important intermediates in lipid metabolism with regulatory properties. Acyl-CoA-binding proteins bind and transport acyl-CoAs to fulfill these functions.
Wei Meng+9 more
doaj +1 more source
Cohomology of coherent sheaves on a proper scheme [PDF]
(Makes a Gamma-acylic coherent resolution of a coherent sheaf on a projection scheme.)
arxiv
Acyl Coenzyme A Thioesterase 7 Regulates Neuronal Fatty Acid Metabolism To Prevent Neurotoxicity
Numerous neurological diseases are associated with dysregulated lipid metabolism; however, the basic metabolic control of fatty acid metabolism in neurons remains enigmatic.
J. Ellis, G. Wong, M. Wolfgang
semanticscholar +1 more source
Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities
Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan+13 more
wiley +1 more source
Correcting a SHAPE-directed RNA structure by a mutate-map-rescue approach [PDF]
The three-dimensional conformations of non-coding RNAs underpin their biochemical functions but have largely eluded experimental characterization. Here, we report that integrating a classic mutation/rescue strategy with high-throughput chemical mapping enables rapid RNA structure inference with unusually strong validation. We revisit a paradigmatic 16S
arxiv +1 more source
Actinobacterial Acyl Coenzyme A Synthetases Involved in Steroid Side-Chain Catabolism
Bacterial steroid catabolism is an important component of the global carbon cycle and has applications in drug synthesis. Pathways for this catabolism involve multiple acyl coenzyme A (CoA) synthetases, which activate alkanoate substituents for β ...
Israël Casabon+4 more
semanticscholar +1 more source
First Steps toward the Design of Peptides that Influence the Intracellular Palmitoylation Machinery
Herein, DC peptides consisting of the cell‐penetrating peptide sC18* and a Asp–His–His–Cys (DHHC) motif derived from human ZDHHC palmitoyltransferase are highlighted. DC peptides demonstrate high cellular internalization into various cellular models, exert cytotoxic effects against cancerous cells, and alter the function and localization of known ...
Katharina Stillger+7 more
wiley +1 more source
Distinct isoforms of long-chain acyl-CoA synthetases (ACSLs) may partition fatty acids toward specific metabolic cellular pathways. For each of the five members of the rat ACSL family, we analyzed tissue mRNA distributions, and we correlated the mRNA ...
Douglas G. Mashek+2 more
doaj
Development of Carbon-Fiber Electrodes Modified for Electrochemical ATP Detection [PDF]
Adenosine triphosphate (ATP) is a highly energetic molecule used as a coenzyme in the transfer of chemical energy required for the continuation of cellular metabolism. In addition, extracellular ATP has an important role in cell-to-cell communication in immune, nervous and vascular systems.
arxiv
Gradient-based Causal Structure Learning with Normalizing Flow [PDF]
In this paper, we propose a score-based normalizing flow method called DAG-NF to learn dependencies of input observation data. Inspired by Grad-CAM in computer vision, we use jacobian matrix of output on input as causal relationships and this method can be generalized to any neural networks especially for flow-based generative neural networks such as ...
arxiv