Results 111 to 120 of about 2,608,587 (304)
Applied and Environmental Microbiology, 2013 Triacylglycerols and wax esters are synthesized as energy storage molecules by some proteobacteria and actinobacteria under stress. The enzyme responsible for neutral lipid accumulation is the bifunctional wax ester synthase/acyl-coenzyme A (CoA ...
Juan A. Villa +3 more
semanticscholar +1 more source
Journal of Lipid Research, 2009 Long-chain acylcarnitines accumulate in long-chain fatty acid oxidation defects, especially during periods of increased energy demand from fat. To test whether this increase in long-chain acylcarnitines in very long-chain acyl-CoA dehydrogenase (VLCAD−/−)
Frank ter Veld +4 more
doaj
Physical System for Non Time Sequence Data [PDF]
arXiv, 2020 We propose a novelty approach to connect machine learning to causal structure learning by jacobian matrix of neural network w.r.t. input variables. In this paper, we extend the jacobian-based approach to physical system which is the method human explore and reason the world and it is the highest level of causality. By functions fitting with Neural ODE,
arxiv
Journal of Lipid Research, 2012 Our goal was to assess the validity of the enrichments of plasma free palmitate and intramuscular (IM) fatty acid metabolites as precursors for calculating the IM triglyceride fractional synthetic rate.
Xiao-jun Zhang +7 more
doaj
Rat Intestinal Acyl Coenzyme A: Cholesterol Acyl Transferase Properties and Localization
Experimental Biology and Medicine, 1984 Microsomal acyl coenzyme A:cholesterol acyltransferase activity of rat intestinal mucosa was measured as the incorporation of [1-14C]oleic acid into cholesterol esters. Exogenous cholesterol and sterol carrier protein singly and together extended the time over which the reaction rate was linear. Cholesterol esterification was suppressed by 2-monooleoyl
George V. Vahouny +2 more
openaire +3 more sources
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
A Chemo-Enzymatic Road Map to the Synthesis of CoA Esters
Molecules, 2016 Coenzyme A (CoA) is a ubiquitous cofactor present in every known organism. The thioesters of CoA are core intermediates in many metabolic processes, such as the citric acid cycle, fatty acid biosynthesis and secondary metabolism, including polyketide ...
Dominik M. Peter +3 more
doaj +1 more source
Glia, EarlyView.CoPAN affects CoA biosynthesis and leads to iron dyshomeostasis. CoPAN d‐astrocytes show ferroptosis, iron accumulation, senescence, lipid peroxidation, mitochondrial damage and tubulin acetylation loss. Astrocytes recapitulate CoPAN disease. ABSTRACT COASY protein‐associated neurodegeneration (CoPAN) is a rare autosomal recessive disorder within the ...
Anna Cozzi +8 more
wiley +1 more source
Electron spin and the origin of Bio-homochirality I. Extant enzymatic reaction model [PDF]
arXiv, 2013 In this paper, I tentatively put forward a new hypothesis that the emergence of a single chiral form of biomolecules in living organisms is specifically determined by the electron spin state during their enzyme-catalyzed synthesis processes. Specifically speaking, the electrons released from the coenzyme NAD(P)H of amino acid synthase are heterogeneous
arxiv
Plant Physiology, 2012 The Arabidopsis (Arabidopsis thaliana) acyl-coenzyme A (CoA) desaturase-like (ADS) gene family contains nine genes encoding fatty acid desaturase-like proteins. The biological function of only one member of the family, fatty acid desaturase5 (AtADS3/FAD5,
Mark A. Smith +8 more
semanticscholar +1 more source