Results 141 to 150 of about 2,608,587 (304)

Impact of Lipid Structural Variations on Bilayer Properties: A Coarse-Grained Molecular Dynamics Study [PDF]

arXiv
The supramolecular assembly of lipids into bilayer membranes is essential for cellular structure and function. However, the impact of lipid structural variations such as acyl chain length, degree of unsaturation, and headgroup type on bilayer properties remains incompletely understood.
arxiv  

Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A. [PDF]

Nat Commun, 2023
Lee BH, De Jesús Pérez JJ, Moiseenkova-Bell V, Rohacs T.   +3 more
europepmc   +1 more source

The Inhibition of the Fatty Acid Synthetase Multienzyme Complex of Yeast by Long‐Chain Acyl Coenzyme A Compounds [PDF]

, 1968
G. Lust, Fréderic Lynen
openalex   +1 more source

HLH‐30/TFEB Rewires the Chaperone Network to Promote Proteostasis Upon Perturbations to the Coenzyme A and Iron–Sulfur Cluster Biosynthesis Pathways

Aging Cell, EarlyView.
Proteostasis enhancing treatments are potential therapies for many age‐related diseases. We discovered that interference with the CoA biosynthesis pathway and limiting iron‐sulfur cluster availability improve proteostasis in C. elegans. Proteostasis improvement under these conditions depends on the conserved HLH‐30/TFEB transcription factor, which ...
Rewayd Shalash, Dror Michael Solomon, Mor Levi‐Ferber, Henrik von Chrzanowski, Mohammad Khaled Atrash, Barak Nakar, Matan Yosef Avivi, Hagit Hauschner, Aviya Swisa, Alicia Meléndez, Yaron Shav‐Tal, Sivan Henis‐Korenblit   +11 more
wiley   +1 more source

Ligand binding to the ACBD6 protein regulates the acyl-CoA transferase reactions in membranes

Journal of Lipid Research, 2015
The binding determinants of the human acyl-CoA binding domain-containing protein (ACBD) 6 and its function in lipid renewal of membranes were investigated. ACBD6 binds acyl-CoAs of a chain length of 6 to 20 carbons.
Eric Soupene, Frans A. Kuypers
doaj  

Independence Posets [PDF]

arXiv, 2018
Let $G$ be an acylic directed graph. For each vertex $g \in G$, we define an involution on the independent sets of $G$. We call these involutions flips, and use them to define a new partial order on independent sets of $G$. Trim lattices generalize distributive lattices by removing the graded hypothesis: a graded trim lattice is a distributive ...
arxiv  

Acyl coenzyme A binding protein (ACBP): An aging- and disease-relevant "autophagy checkpoint". [PDF]

Aging Cell, 2023
Montégut L, Abdellatif M, Motiño O, Madeo F, Martins I, Quesada V, López-Otín C, Kroemer G.   +7 more
europepmc   +1 more source

Role for the liver X receptor agonist 22‐ketositosterol in preventing disease progression in an Alzheimer's disease mouse model

British Journal of Pharmacology, EarlyView.
Background and Purpose Liver X receptors (LXRs) are promising therapeutic targets for alleviating Alzheimer's disease (AD) symptoms. We assessed the impact of the semi‐synthetic LXR agonist 22‐ketositosterol on disease progression in an AD mouse model.
Nikita Martens, Na Zhan, Sammie C. Yam, Marcella Palumbo, Lorenzo Pontini, Frank P. J. Leijten, Leonie van Vark‐van der Zee, Gardi Voortman, Silvia Friedrichs, Albert Gerding, Maura Marinozzi, Johan W. Jonker, Folkert Kuipers, Dieter Lütjohann, Tim Vanmierlo, Monique T. Mulder   +15 more
wiley   +1 more source

Multi-Method Quantification of Acetyl-Coenzyme A and Further Acyl-Coenzyme A Species in Normal and Ischemic Rat Liver. [PDF]

Int J Mol Sci, 2023
Tokarska-Schlattner M, Zeaiter N, Cunin V, Attia S, Meunier C, Kay L, Achouri A, Hiriart-Bryant E, Couturier K, Tellier C, El Harras A, Elena-Herrmann B, Khochbin S, Le Gouellec A, Schlattner U.   +14 more
europepmc   +1 more source

Studies on medium-chain fatty acyl-coenzyme A synthetase. Enzyme fraction I: mechanism of reaction and allosteric properties [PDF]

, 1968
Jacob Bar‐Tana, G. Rose
openalex   +1 more source