Results 171 to 180 of about 2,608,587 (304)

Long-Chain Acyl Coenzyme A Dehydrogenase, a Key Player in Metabolic Rewiring/Invasiveness in Experimental Tumors and Human Mesothelioma Cell Lines. [PDF]

open access: yesCancers (Basel), 2023
Pouliquen DL   +9 more
europepmc   +1 more source

Enhancing Crop Nutrition in Arid and Semiarid Regions of Africa Through Genome Editing Using CRISPR/Cas

open access: yesFood and Energy Security, Volume 14, Issue 3, May/June 2025.
ABSTRACT Food insecurity is a pressing issue in Africa, aggravated by escalating drought, jeopardizing the region's ability to meet nutritional requirements for human health. In arid and semiarid regions, crop yield is severely affected by drought and salinity.
Erick Amombo   +5 more
wiley   +1 more source

iPSC‐Derived Liver Organoids as a Tool to Study Medium Chain Acyl‐CoA Dehydrogenase Deficiency

open access: yesJournal of Inherited Metabolic Disease, Volume 48, Issue 3, May 2025.
ABSTRACT Medium chain acyl‐CoA dehydrogenase deficiency (MCADD) is an inherited metabolic disease, characterized by biallelic variants in the ACADM gene. Interestingly, even with the same genotype, patients often present with very heterogeneous symptoms, ranging from fully asymptomatic to life‐threatening hypoketotic hypoglycemia.
Ligia A. Kiyuna   +13 more
wiley   +1 more source

Immunodepletion experiments suggest that acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1) protein plays a major catalytic role in adult human liver, adrenal gland, macrophages, and kidney, but not in intestines

open access: yesJournal of Lipid Research, 1998
The first acyl-coenzyme A:cholesterol acyltransferase (ACAT) cDNA cloned and expressed in 1993 is designated as ACAT-1. In various human tissue homogenates, ACAT-1 protein is effectively solubilized with retention of enzymatic activity by the detergent ...
Oneil Lee   +3 more
doaj  

Selective Transfer of Cyclopropane Acids by Acyl Coenzyme A:Phospholipid Acyltransferases

open access: hybrid, 1969
Harumi Okuyama   +3 more
openalex   +1 more source

The Ever‐Expanding Influence of the Endothelial Nitric Oxide Synthase

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 136, Issue 5, May 2025.
ABSTRACT Nitric oxide (NO) generated by the endothelial NO synthase (eNOS) plays an essential role in the maintenance of vascular homeostasis and the prevention of vascular inflammation. There are a myriad of mechanisms that regulate the activity of the enzyme that may prove to represent interesting therapeutic opportunities.
Riham Rafea   +2 more
wiley   +1 more source

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