Results 181 to 190 of about 2,608,587 (304)

Carnitine supplementation improves insulin sensitivity and skeletal muscle acetylcarnitine formation in patients with type 2 diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2864-2877, May 2025.
Abstract Aim/Hypothesis Recently, we reported that increasing free carnitine availability resulted in elevated skeletal muscle acetylcarnitine concentrations and restored metabolic flexibility in individuals who have impaired glucose tolerance. Metabolic flexibility is defined as the capacity to switch from predominantly fat oxidation while fasted to ...
Yvonne M. H. Op den Kamp‐Bruls   +14 more
wiley   +1 more source

Surviving on Limited Resources: Effects of Caloric Restriction on Growth, Gene Expression and Gut Microbiota in a Species With Male Pregnancy (Hippocampus erectus)

open access: yesMolecular Ecology, Volume 34, Issue 9, May 2025.
ABSTRACT Caloric restriction (CR) studies have traditionally focused on species with conventional reproductive roles, emphasising female's greater investment in costly gametes and parental care. While the divergent impact of CR on males and females is evident across species, the factors driving this variation, that is, resource allocation to ...
Freya Adele Pappert   +3 more
wiley   +1 more source

Structural Basis of Cyclic 1,3-Diene Forming Acyl-Coenzyme A Dehydrogenases. [PDF]

open access: yesChembiochem, 2021
Kung JW   +6 more
europepmc   +1 more source

Repeated colonisation of alpine habitats by Arabidopsis arenosa involved parallel adjustments of leaf cuticle traits

open access: yesNew Phytologist, Volume 246, Issue 4, Page 1597-1608, May 2025.
Summary Cuticle function can be pivotal to plant success in different environments. Yet, the occurrence of intraspecific adjustments in cuticle traits resulting from acclimation or adaptation to different habitats remains poorly understood. Here, we used genetically well‐characterised populations of Arabidopsis arenosa to investigate whether cuticle ...
Clara Bertel   +11 more
wiley   +1 more source

Long-chain acyl-CoA synthetase isoforms differ in preferences for eicosanoid species and long-chain fatty acids[S]

open access: yesJournal of Lipid Research, 2017
Because the signaling eicosanoids, epoxyeicosatrienoic acids (EETs) and HETEs, are esterified to membrane phospholipids, we asked which long-chain acyl-CoA synthetase (ACSL) isoforms would activate these molecules and whether the apparent FA substrate ...
Eric L. Klett   +4 more
doaj  

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