Results 181 to 190 of about 89,084 (326)

Acyl Coenzyme A:1-Acylglycerophosphorylglycerol Acyltransferase from Rat Liver

open access: yesJournal of Biological Chemistry, 1973
Abstract Rat liver microsomes are capable of catalyzing the acylation of 1-palmitoyl-sn-glycero-3-phosphoryl-rac-glycerol for phosphatidylglycerol formation. The requirements for the reaction appear to be the same as the analogous reaction for lecithin synthesis.
openaire   +2 more sources

The Crystal Structure of Human Transport and Golgi Organization 2 Homolog (TANGO2) Protein Reveals an αββα‐Fold Arrangement

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 2, Page 515-528, February 2026.
ABSTRACT Transport and Golgi Organization 2 Homolog (TANGO2) protein deficiency disorder (TDD) is a rare autosomal recessive disorder characterized by multi‐systemic abnormalities and significant phenotypic variability including neurodevelopmental delay, seizures, intermittent ataxia, hypothyroidism, rhabdomyolysis, life‐threatening metabolic ...
Anne Cooper   +6 more
wiley   +1 more source

Comparative lipidomic and proteomic analysis reveals species‐specific differences in midgut composition and insecticide absorption between Apis mellifera and Bombus terrestris

open access: yesPest Management Science, Volume 82, Issue 2, Page 1540-1551, February 2026.
Lipidomic and proteomic analysis revealed large‐scale differences in the midgut composition of the honeybee Apis mellifera and the buff‐tailed bumblebee Bombus terrestris. These differences correlated to increased insecticide absorption in the bumblebee when using an ex vivo Ussing chamber and subsequently in vivo feeding assay (created in Biorender ...
Emmanouil Kokkas   +7 more
wiley   +1 more source

Binding to medium and long chain fatty acyls is a common property of HEAT and ARM repeat modules. [PDF]

open access: yes, 2019
Covalent post-translational modification (PTM) of proteins with acyl groups of various carbon chain-lengths regulates diverse biological processes ranging from chromatin dynamics to subcellular localization.
Chua, Katrin F   +7 more
core   +1 more source

Synechococcus Under Stress: Contrasting Physiological and Transcriptional Responses to Salinity and Temperature in Marine Versus Euryhaline Strains

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Two model strains of Synechococcus sp.—the marine RS9907 and the euryhaline WH5701—exhibit distinct physiological responses to salinity after long acclimations at optimal and cold growth temperatures. Transcriptomic and photochemical analyses reveal drastic differences in their regulatory strategies and photosynthetic activity across a salinity ...
Isabel Escribano‐Gómez   +6 more
wiley   +1 more source

Deciphering the Transcriptomic Signatures of Aging Across Organs in Mice

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Comprehensive transcriptomic profiling of eight mouse organs across six ages reveals how aging reshapes biological processes. Trajectory and network analyses distinguish shared and organ‐specific signatures, charting the molecular landscape of systemic aging.
Sarah Morsy   +9 more
wiley   +1 more source

TMEM120A maintains adipose tissue lipid homeostasis through ER CoA channeling

open access: yesNature Communications
Efficient fatty acid (FA) re-esterification is essential for lipid homeostasis in adipocytes, yet the mechanisms coordinating Coenzyme A (CoA) availability at the endoplasmic reticulum (ER)—a major site of lipid synthesis—remain unclear.
Yoon Keun Cho   +18 more
doaj   +1 more source

Lifespan‐Extending Endogenous Metabolites

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

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