Results 51 to 60 of about 89,084 (326)

Clinical and Gene Analysis of Fatty Acid Oxidation Disorders Found in Neonatal Tandem Mass Spectrometry Screening

open access: yesPharmacogenomics and Personalized Medicine, 2023
Xiaoxia Wang, Haining Fang Department of Pediatrics, Maternal and Child Health Hospital of Hubei Province, Wuhan, 430070, People’s Republic of ChinaCorrespondence: Haining Fang, Department of Pediatrics, Maternal and Child Health Hospital of Hubei ...
Wang X, Fang H
doaj  

Rat long-chain acyl-CoA synthetase mRNA, protein, and activity vary in tissue distribution and in response to diet

open access: yesJournal of Lipid Research, 2006
Distinct isoforms of long-chain acyl-CoA synthetases (ACSLs) may partition fatty acids toward specific metabolic cellular pathways. For each of the five members of the rat ACSL family, we analyzed tissue mRNA distributions, and we correlated the mRNA ...
Douglas G. Mashek   +2 more
doaj   +1 more source

Molecular Basis of KAT2A Selecting Acyl-CoA Cofactors for Histone Modifications

open access: yesResearch, 2023
Emerging discoveries about undocumented acyltransferase activities of known histone acetyltransferases (HATs) advance our understandings in the regulation of histone modifications. However, the molecular basis of HATs selecting acyl coenzyme A (acyl-CoA)
Sha Li   +7 more
doaj   +1 more source

Corresponding increase in long-chain acyl-CoA and acylcarnitine after exercise in muscle from VLCAD mice

open access: yesJournal of Lipid Research, 2009
Long-chain acylcarnitines accumulate in long-chain fatty acid oxidation defects, especially during periods of increased energy demand from fat. To test whether this increase in long-chain acylcarnitines in very long-chain acyl-CoA dehydrogenase (VLCAD−/−)
Frank ter Veld   +4 more
doaj   +1 more source

Identification of a Novel Self-Sufficient Styrene Monooxygenase from Rhodococcus opacus 1CP. [PDF]

open access: yes, 2009
Sequence analysis of a 9-kb genomic fragment of the actinobacterium Rhodococcus opacus 1CP led to identification of an open reading frame encoding a novel fusion protein, StyA2B, with a putative function in styrene metabolism via styrene oxide and ...
Berkel, W.J.H., van   +5 more
core   +4 more sources

Biosynthesis of α-Tocopherol and Plastoquinone-9 in spinach chloroplasts [PDF]

open access: yes, 1980
Prenylation and methylation reaction in al biosynthesis is localized in the envelope membranes of the chloroplasts, while PQ-9 biosynthesis takes place in the envelope membranes and also in the thylakoid membranes.
Mazliak, P.   +2 more
core   +1 more source

Arachidonoyl-carnitine and arachidonoyl-coenzyme A are suitable substrates for mammalian ALOX isoforms

open access: yesJournal of Lipid Research
Lipoxygenases (ALOX) convert free polyenoic fatty acids to bioactive mediators, which induce phenotypic alterations in target cells. However, the intracellular concentrations of free fatty acids are very low, as these compounds are rapidly esterified ...
Xin Chen   +8 more
doaj   +1 more source

Measurement of precursor enrichment for calculating intramuscular triglyceride fractional synthetic rate

open access: yesJournal of Lipid Research, 2012
Our goal was to assess the validity of the enrichments of plasma free palmitate and intramuscular (IM) fatty acid metabolites as precursors for calculating the IM triglyceride fractional synthetic rate.
Xiao-jun Zhang   +7 more
doaj   +1 more source

Characterization of a Bifunctional Archaeal Acyl Coenzyme A Carboxylase [PDF]

open access: yesJournal of Bacteriology, 2003
ABSTRACT Acyl coenzyme A carboxylase (acyl-CoA carboxylase) was purified from Acidianus brierleyi . The purified enzyme showed a unique subunit structure (three subunits with apparent molecular masses of 62, 59, and 20 kDa) and a molecular mass of approximately 540 kDa, indicating an α 4
Songkran, Chuakrut   +3 more
openaire   +2 more sources

Insights into molecular mechanisms of disease in Neurodegeneration with Brain Iron Accumulation; unifying theories. [PDF]

open access: yes, 2016
Neurodegeneration with brain iron accumulation (NBIA) is a group of disorders characterised by dystonia, parkinsonism and spasticity. Iron accumulates in the basal ganglia and may be accompanied by Lewy bodies, axonal swellings and hyperphosphorylated ...
Adibhatla   +148 more
core   +1 more source

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