Results 61 to 70 of about 89,084 (326)
Journal of Biological Chemistry, 1973 Abstract A particulate preparation isolated from Escherichia coli B catalyzes the acylation of 1-acyl-sn-glycerol 3-phosphate (1-acyl-GP) with both oleoyl-CoA and palmitoyl-CoA. The optimum conditions were determined for the acyl-CoA: 1-acyl-GP acyltransferase.
H, Okuyama, S J, Wakil
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Purification and Characterization of a Novel Pumpkin Short-Chain Acyl-Coenzyme A Oxidase with Structural Similarity to Acyl-Coenzyme A Dehydrogenases [PDF]
Plant Physiology, 2000 Abstract A novel pumpkin (Cucurbita pepo) short-chain acyl-coenzyme A (CoA) oxidase (ACOX) was purified to homogeneity by hydrophobic-interaction, hydroxyapatite, affinity, and anion-exchange chromatography. The purified enzyme is a tetrameric protein, consisting of apparently identical 47-kD subunits.
DE BELLIS L. +5 more
openaire +3 more sources
PLoS ONE, 2016 Dysregulated lipid metabolism contributes to cancer progression. Our previous study indicates that long-chain fatty acyl-Co A synthetase (ACSL) 3 is essential for lipid upregulation induced by endoplasmic reticulum stress.
Wei-Ching Chen +5 more
semanticscholar +1 more source
Remnants of an ancient metabolism without phosphate [PDF]
, 2017 Phosphate is essential for all living systems, serving as a building block of genetic and metabolic machinery. However, it is unclear how phosphate could have assumed these central roles on primordial Earth, given its poor geochemical accessibility.
Goldford, Joshua E. +3 more
core +1 more source
Control of fatty acid distribution in phosphatidylcholine of spinach leaves
Journal of Lipid Research, 1971 The acylation of lysophosphatidylcholine by enzyme preparations from spinach leaves was studied. The acylation reaction was followed by the incorporation of 14C-labeled fatty acids from the respective coenzyme A derivatives into phosphatidylcholine.
K.A. DEVOR, J.B. MUDD
doaj +1 more source
Plants, 2020 The spectral quality and intensity of light, photoperiodism, and other environmental factors have profound impacts on the metabolic composition of light-dependent higher plants.
Muthusamy Muthusamy +10 more
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A Single LC-MS/MS Analysis to Quantify CoA Biosynthetic Intermediates and Short-Chain Acyl CoAs
Metabolites, 2021 Coenzyme A (CoA) is an essential cofactor for dozens of reactions in intermediary metabolism. Dysregulation of CoA synthesis or acyl CoA metabolism can result in metabolic or neurodegenerative disease.
Anthony E. Jones +5 more
doaj +1 more source
CoA protects against the deleterious effects of caloric overload in Drosophila [PDF]
, 2016 We developed a Drosophila model of T2D in which high sugar (HS) feeding leads to insulin resistance. In this model, adipose TG storage is protective against fatty acid toxicity and diabetes.
Baranski, Thomas J +2 more
core +2 more sources
Structure and substrate selectivity of the 750-kDa α6β6 holoenzyme of geranyl-CoA carboxylase. [PDF]
, 2015 Geranyl-CoA carboxylase (GCC) is essential for the growth of Pseudomonas organisms with geranic acid as the sole carbon source. GCC has the same domain organization and shares strong sequence conservation with the related biotin-dependent carboxylases 3 ...
Huang, Christine S +4 more
core +2 more sources
eLife, 2013 Large Ca transients cause massive endocytosis (MEND) in BHK fibroblasts by nonclassical mechanisms. We present evidence that MEND depends on mitochondrial permeability transition pore (PTP) openings, followed by coenzyme A (CoA) release, acyl CoA ...
Donald W Hilgemann +4 more
doaj +1 more source