Results 61 to 70 of about 31,267 (192)
A microfluorometric method for the determination of free fatty acids in plasma
A rapid and precise microfluorometric method for the determination of free fatty acid concentrations in 2-5 microliters of plasma is described. The assay is performed directly on plasma, eliminating the need for extraction with organic solvents, and is ...
J Miles+4 more
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Rat Intestinal Acyl Coenzyme A: Cholesterol Acyl Transferase Properties and Localization
Microsomal acyl coenzyme A:cholesterol acyltransferase activity of rat intestinal mucosa was measured as the incorporation of [1-14C]oleic acid into cholesterol esters. Exogenous cholesterol and sterol carrier protein singly and together extended the time over which the reaction rate was linear. Cholesterol esterification was suppressed by 2-monooleoyl
George V. Vahouny+2 more
openaire +3 more sources
A Chemo-Enzymatic Road Map to the Synthesis of CoA Esters
Coenzyme A (CoA) is a ubiquitous cofactor present in every known organism. The thioesters of CoA are core intermediates in many metabolic processes, such as the citric acid cycle, fatty acid biosynthesis and secondary metabolism, including polyketide ...
Dominik M. Peter+3 more
doaj +1 more source
Autoacylation of myelin proteolipid protein with acyl coenzyme A.
Rat brain myelin proteolipid protein (PLP) is known to contain long chain, covalently bound fatty acids. In the course of characterizing the mechanism of acylation, we found that the isolated PLP, in the absence of any membrane fraction, was esterified after incubation with [3H]palmitoyl coenzyme A (CoA).
Marjorie B. Lees+2 more
openaire +3 more sources
Because the signaling eicosanoids, epoxyeicosatrienoic acids (EETs) and HETEs, are esterified to membrane phospholipids, we asked which long-chain acyl-CoA synthetase (ACSL) isoforms would activate these molecules and whether the apparent FA substrate ...
Eric L. Klett+4 more
doaj +1 more source
Human acyl-coenzyme A binding domain-containing member 6 (ACBD6) is a modular protein that carries an acyl-CoA binding domain at its N terminus and two ankyrin motifs at its C terminus.
Eric Soupene+2 more
doaj +1 more source
Effect of pregnancy and lactation on lipoprotein and cholesterol metabolism in the rat
Origins of hyperlipidemia and cholestasis that occur during pregnancy were investigated by examining expression of key elements related to plasma and hepatic cholesterol metabolism during pregnancy, lactation, and post-lactation in the rat model.
Jeffery L. Smith+5 more
doaj +1 more source
The Inhibition of the Fatty Acid Synthetase Multienzyme Complex of Yeast by Long‐Chain Acyl Coenzyme A Compounds [PDF]
G. Lust, Frédéric Lynen
openalex +1 more source
Studies on medium-chain fatty acyl-coenzyme A synthetase. Enzyme fraction I: mechanism of reaction and allosteric properties [PDF]
Jacob Bar‐Tana, G. Rose
openalex +1 more source
Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A. [PDF]
Lee BH+3 more
europepmc +1 more source