Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of methyl salicylate [09.749] obtained by steam distillation from the leaves of Gaultheria procumbens L. when used as a sensory additive in feed for all animal species except cats. The EFSA Panel on Additives and Products
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +23 more
wiley +1 more source
π‐Extended Silyl Enolates as Emerging Platforms in Radical Chemistry
This review covers the emerging role of π‐extended silyl polyenol ethers in radical chemistry. It highlights their versatile roles as electron‐rich SOMOphiles, silyl radical cation precursors, and nucleophilic partners in radical–polar crossover manifolds, while considering recent advances in photoredox catalysis, electrochemistry, and transition metal‐
Debora Guazzetti +3 more
wiley +1 more source
Nucleophilic Trifluoromethoxylation of Acyl Chlorides: A Direct Route to Trifluoromethyl Esters
A new method for the synthesis of the underexplored trifluoromethyl carboxylic esters using acyl chlorides as readily available feedstocks and in situ‐generated AgOCF3 from silver fluoride and the trifluoromethyl para‐toluenesulfonate has been designed. The reaction works on a large variety of aromatic and aliphatic acyl chlorides, while minimizing the
Xavier Bertrand +3 more
wiley +1 more source
Recent Applications of Propylene Carbonate as a Solvent in Sustainable Organic Synthesis
This review evaluates propylene carbonate (PC) as a non‐toxic green solvent in organic synthesis, highlighting its performance in key reactions including cross‐couplings, asymmetric hydrogenations, peptide synthesis and biocatalysis. Across these processes, PC delivers yields comparable to conventional and alternative green solvents.
Laura G. Aguilar‐Sanchez +1 more
wiley +1 more source
Precision Chemistry for Protein Lysine Modification
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley +1 more source
AgBF<sub>4</sub>-catalyzed insertion of unactivated alkynes into C-F bonds of acyl fluorides. [PDF]
Emmei T, Tobisu M.
europepmc +1 more source
Fe-LMCT Photodecarboxylation for (Hetero)arene Chloro- and Bromodifluoromethylation: Rapid Access to Aromatic Acyl Fluorides. [PDF]
Fernández-García S +2 more
europepmc +1 more source
Chemoselective Cu-catalyzed acylsilylation of vinyl arenes using silylboronates and acyl fluorides. [PDF]
Zhao Z +4 more
europepmc +1 more source
Direct Synthesis of Various Thioesters from Acyl Fluorides and Thiosilanes through the Assistance of a Si-F Bond Formation. [PDF]
Takeuchi R, Ishida K, Sakai N.
europepmc +1 more source
Palladium-Catalyzed Decarbonylative Alkylation of Acyl Fluorides
Palladium-catalyzed decarbonylative alkylation reactions of acyl fluorides have been developed using alkylboranes having β-hydrogens. A wide range of functional groups were well tolerated, even at the high temperature required for decarbonylation. This protocol provides a diverse C(sp2)–C(sp3) bond formation via a highly efficient decarbonylative ...
openaire +1 more source

