Results 311 to 320 of about 63,314 (347)
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[7] Coenzyme a-independent acyltransferase
1992Publisher Summary This chapter describes coenzyme A-independent acyltransferase. The coenzyme A (CoA)-independent transacylation system catalyzes the transfer of fatty acids from diradyl phospholipids to various lysophospholipids in the absence of any cofactors, differing from the CoA-dependent transacylation reaction, which requires the presence of ...
Takayuki Sugiura, Keizo Waku
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A review on lecithin:cholesterol acyltransferase deficiency.
Clinical Biochemistry, 2015Lecithin cholesterol acyl transferase (LCAT) is a plasma enzyme which esterifies cholesterol, and plays a key role in the metabolism of high-density lipoprotein cholesterol (HDL-C). Genetic disorders of LCAT are associated with lipoprotein abnormalities including low levels of HDL-C and presence of lipoprotein X, and clinical features mainly corneal ...
R. Saeedi, Min Li, J. Frohlich
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[10] Dihydroxyacetone phosphate acyltransferase
1992Publisher Summary Dihydroxyacetone phosphate acyltransferase (DHAPAT) catalyzes the transfer of the fatty acid moiety from long-chain acyl-coenzyme A (acyl-CoA) to the free hydroxyl group of dihydroxyacetone phosphate. This reaction initiates the synthesis of the ether-linked glycerolipids and the more common glycerol ester lipids.
Keith O. Webber, Amiya K. Hajra
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Serine carboxypeptidase-like acyltransferases
Phytochemistry, 2004In plant secondary metabolism, an alternative pathway of ester formation is facilitated by acyltransferases accepting 1-O-beta-acetal esters (1-O-beta-glucose esters) as acyl donors instead of coenzyme A thioesters. Molecular data indicate homology of these transferases with hydrolases of the serine carboxypeptidase type defining them as serine ...
Dieter Strack, Carsten Milkowski
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Mechanism and function of DHHC S-acyltransferases
Biochemical Society Transactions, 2013Protein S-palmitoylation is a reversible post-translational modification of proteins with fatty acids. In the last 5 years, improved proteomic methods have increased the number of proteins identified as substrates for palmitoylation from tens to hundreds.
Benjamin C. Jennings, Maurine E. Linder
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Physiological Functions of Phospholipid:Diacylglycerol Acyltransferases
Plant And Cell Physiology, 2023Abstract Triacylglycerol (TAG) is among the most energy dense storage forms of reduced carbon in living systems. TAG metabolism plays critical roles in cellular energy balance, lipid homeostasis, cell growth and stress responses. In higher plants, microalgae and fungi, TAG is assembled by acyl-CoA-dependent and acyl-CoA-independent ...
Saroj Kumar Sah+4 more
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[11] Diacylglycerol acyltransferase and monoacylglycerol acyltransferase from liver and intestine
1992Publisher Summary The acylation of diacylglycerol catalyzed by the diacylglycerol acyltransferase is the only enzyme reaction unique to triacylglycerol synthesis. This reaction lies at the diacylglycerol branch point of phosphatidylcholine, phosphatidylethanolamine, and triacylglycerol synthesis.
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Inhibition of acyltransferase in lymphocytes by concanavalin A
Biochimica et Biophysica Acta (BBA) - General Subjects, 1980The effects of concanavalin A and succinylated concanavalin A on the transformation of mouse splenic lymphocytes, and on early biochemical events in the transformation, were compared. 1. The transformation of lymphocytes is biphasic with respect to concanavalin A concentration with optimal activation at about 1 microgram/ml.
Alan Mellors, Paul Dobson
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What makes a lipase a valuable acyltransferase in water abundant medium
, 2017The necessity to develop more eco-friendly processes in oleochemistry has recently led to a renewed consideration of lipases exhibiting high acyltransferase activity in hydrated media.
M. Subileau+5 more
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Enhancing the Acyltransferase Activity of Candida antarctica Lipase A by Rational Design
ChemBioChem, 2015A few lipases, such as Candida antarctica lipase A (CAL‐A), are known to possess acyltransferase activity. This enables the enzyme to synthesize fatty acid esters from natural oils and alcohols even in the presence of bulk water.
Janett Müller+4 more
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