The Evolutionary Dynamics of Genetic Mutational Load Throughout Tomato Domestication History
ABSTRACT Understanding the impact of domestication on deleterious mutations has fascinated evolutionary biologists and breeders alike. A ‘cost of domestication’ has been reported for some organisms through accumulation of gene disruptions or radical amino acid changes.
Hamid Razifard+6 more
wiley +1 more source
Carnitine O-Acetyltransferase as a Central Player in Lipid and Branched-Chain Amino Acid Metabolism, Epigenetics, Cell Plasticity, and Organelle Function. [PDF]
Volpicella M+7 more
europepmc +1 more source
Defining the Enterococcus faecalis Fatty Acid Kinase System of Exogeneous Fatty Acid Utilization
The enteric bacterium Enterococcus faecalis incorporates fatty acids from the medium and elongates any short chains to lengths suitable for membrane lipids. We have delineated the pathway. ABSTRACT Phospholipid synthesis in Firmicute bacteria differs markedly from that of the paradigm Escherichia coli pathway in that acyl phosphates are a key ...
Huijuan Dong, Qi Zou, John E. Cronan
wiley +1 more source
Recent Progress in <i>N</i>-Acylethanolamine Research: Biological Functions and Metabolism Regulated by Two Distinct <i>N</i>-Acyltransferases: cPLA<sub>2</sub>ε and PLAAT Enzymes. [PDF]
Uyama T+3 more
europepmc +1 more source
Local adaptation of both plant and pathogen: an arms‐race compromise in switchgrass rust
Summary In coevolving species, parasites locally adapt to host populations as hosts locally adapt to resist parasites. Parasites often outpace host local adaptation since they have rapid life cycles, but host diversity, the strength of selection, and external environmental influence can result in complex outcomes.
Acer VanWallendael+14 more
wiley +1 more source
Physiological and biochemical effects of different expression of acyl-CoA: lysophosphatidylethanolamine acyltransferases encoding genes observed in arabidopsis plants cultivated under low and standard temperatures. [PDF]
Jasieniecka-Gazarkiewicz K+2 more
europepmc +1 more source
Identification of BAHD‐acyltransferase enzymes involved in ingenane diterpenoid biosynthesis
Summary The plant family Euphorbiaceae is an abundant source of structurally complex diterpenoids, many of which have reported anticancer, anti‐HIV, and anti‐inflammatory activities. Among these, ingenol‐3‐angelate (1a; tradename: Picato®), isolated from Euphorbia peplus, has potent antitumor activity.
Carsten Schotte+10 more
wiley +1 more source
1-Alkyl-sn-glycero-3-phosphate: acyl-CoA acyltransferase in rat brain microsomes.
Patrick J. Fleming, A K Hajra
openalex +1 more source