Results 231 to 240 of about 32,557 (330)

Lipid Droplet‐Derived Biomimetic Nanocarriers for the Enhancement of Porcine Intermuscular Fat Content

Advanced Science, Volume 12, Issue 21, June 5, 2025.
The article presents the development of artificial lipid droplets (aLDs) as biomimetic nanocarriers to enhance intramuscular fat (IMF) content in pigs. These aLDs, loaded with oleic acid, significantly increase IMF by up to 35% in muscle tissues without adverse side effects. This innovative approach improves pork quality by enhancing marbling, offering
Pengxiang Zhao, Hongbo Han, Jingjie Hao, Ziwei Yu, Zichen Zhao, Lupeng Chen, Heng Wang, Jian Wu, Zhuqing Ren   +8 more
wiley   +1 more source

In vitro reconstitution reveals substrate selectivity of protein S-acyltransferases. [PDF]

J Biol Chem
Mondal T, Song J, Banerjee A.
europepmc   +1 more source

Roles of Acyl-CoA: Diacylglycerol Acyltransferases 1 and 2 in Triacylglycerol Synthesis and Secretion in Primary Hepatocytes

Arteriosclerosis, Thrombosis and Vascular Biology, 2015
Chen Li, Lena Li, Jihong Lian, R. Watts, Randal C. Nelson, B. Goodwin, R. Lehner   +6 more
semanticscholar   +1 more source

MeCP2 Lactylation Protects against Ischemic Brain Injury by Transcriptionally Regulating Neuronal Apoptosis

Advanced Science, Volume 12, Issue 21, June 5, 2025.
MeCP2 lactylation protects against ischemic stroke by reducing brain infarct volume and improving neurological outcomes. Lactylation at K210/K249 exerts neuroprotective effects by repressing the transcription of apoptosis‐associated genes, including Pdcd4 and Pla2g6. HDAC3 and p300 serve as key regulatory enzymes for MeCP2 lactylation following stroke.
Min Sun, Yuxin Zhang, Rui Mao, Yan Chen, Pinyi Liu, Lei Ye, Siyi Xu, Junqiu Jia, Shu Shu, Huiya Li, Yanping Yin, Shengnan Xia, Yanting Chen, Yun Xu   +13 more
wiley   +1 more source

Impact of the crosstalk between the PTEN and PAFR as well as PAFR and EGFR pathways in cancer. [PDF]

Explor Drug Sci
Thyagarajan A, Sirhan Z, Sahu RP.
europepmc   +1 more source

Effect of liposome composition on the activity of detergent-solubilized acylcoenzyme A: cholesterol acyltransferase.

, 1982
S. Mathur, A A Spector
openalex   +1 more source

High Sugar Induced RCC2 Lactylation Drives Breast Cancer Tumorigenicity Through Upregulating MAD2L1

Advanced Science, Volume 12, Issue 21, June 5, 2025.
This study finds that KAT2A mediates the lactylation modification of the non‐histone protein RCC2 at K124, facilitating the recruitment of free SERBP1 and aiding in the formation of the initial SERBP1‐MAD2L1 complex. SERBP1 enhances the stability of MAD2L1 mRNA and promotes cellular proliferation.
Bowen Zheng, Yunhao Pan, Fengyuan Qian, Diya Liu, Danrong Ye, Bolin Yu, Seng Zhong, Wenfang Zheng, Xuehui Wang, Baian Zhou, Yuying Wang, Lin Fang   +11 more
wiley   +1 more source

Microbial cell factory for butyl butyrate production: Knowledges and perspectives. [PDF]

Microb Biotechnol
Guo X, Ding Y, Chen Y, Fu H, Wang J.
europepmc   +1 more source

Human plasma lecithin-cholesterol acyltransferase. An elucidation of the catalytic mechanism.

, 1986
Matti Jauhiainen, Peter J. Dolphin
openalex   +1 more source

Sex‐specific associations of Roseburia with uric acid metabolism and hyperuricemia risk in females

iMetaOmics, Volume 2, Issue 2, June 2025.
Researchers recruited 623 participants, including 270 females, and used 16S rDNA sequencing to investigate gender differences in hyperuricemia. In healthy females, Roseburia was enriched, positively correlating with estrogen and negatively with uric acid, suggesting it is a potential biomarker affecting uric acid levels in females.
Zhihan Yang, Zeng Zhang, Mohan Chen, Jin Hu, Yingqi Qiu, Shijia Lin, Xiaolu Zhou, Jiachao Zhang, Shuaiming Jiang   +8 more
wiley   +1 more source